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Collagen Supplements And Prostate Cancer

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Immune Modulatory Properties Of Collagen In Cancer

Choosing Supplements for Prostate Cancer Part: 1
  • 1National Center for Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital – Herlev and Gentofte, Herlev, Denmark
  • 2Department of Science and Environment, Roskilde University, Roskilde, Denmark
  • 3Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark

Hydrolysed Collagen Inhibits Tumor Growth

There are numerous published studies showing how Hydrolysed Collagen peptides can inhibit tumor growth.

One such study, conducted by Laing et al., reported HC intake inhibited spontaneous tumor incidence and increase life span in Sprague-dawley rats.

The study showed that HC notably increased the mean life span, the life span of the last 30% of the survivors, and the maximal life span it significantly decreased overall spontaneous tumor incidence of both sexes. The incidence of death from tumors was decreased in HC groups in comparison with the control group of both sexes. Scientists concluded that:

HCs dose-dependently increase life span and decrease spontaneous tumor incidence in Sprague-Dawley rats. Moreover, the antioxidative property of HCs may be responsible for the increased life span and protection against tumor development.

The results of a similar study published in the Journal of Cellular and Molecular Medicine, provide a mechanism underlying antiskin ageing by HCs intake and highlight potential application of HCs as a healthcare supplement to combat cancer and cardiovascular disease by inhibiting platelet release.

The authors of that study comment:

these results provide a possible mechanism underlying the anti tumor effect of Hydrolysed Collagen.

Soy: Questions And Answers

  • What is soy?

    The soybean plant has been grown in Asia for food for hundreds of years. The soybean can be made into products, such as soy milk, miso, tofu, soy flour, and oil.

    Soy foods contain phytochemicals that may have health benefits. Isoflavones are the most widely studied compounds in soy. Major isoflavones in the soybean include genistein, daidzein, and glycitein.

    Isoflavones are phytoestrogens that attach to estrogen receptors found in prostate cancercells. Genistein may affect some processes inside prostate cancer cells that are involved in the growth and spread of cancer.

  • How is soy given or taken?

    Soy may be eaten in food or taken in dietary supplements.

  • Have any laboratory or animal studies been done using soy?

    For information on laboratory and animal studies done using soy, see the Laboratory/Animal/Preclinical Studies section of the health professional version of Prostate Cancer, Nutrition, and Dietary Supplements.

  • Have any studies of soy been done in people?

    Population studies and clinical trials have been done to find out if soy can prevent or treat prostate cancer. The results of these studies have been mixed. Some studies have shown a lower risk of prostate cancer or a change in prostate-specific antigen level, and others have not. The results may be mixed because of the small number of men who participated in the studies and the different types and doses of soy products given.

    Combined population studies

  • Clinical trials

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    Key Takeaways For Patients Getting Radiation Therapy

    • Any supplement, such as vitamins, minerals, and herbal cures, should be discussed with your provider. You should not take any new supplements until you talk about it with your provider.
    • During radiation therapy, you may not need to take supplements you have been prescribed in the past. Again, check with your provider.
    • Some supplements, especially antioxidants, may change how your treatment works.
    • Do not take antioxidants throughout treatment, since there is limited research supporting their use.
    • The number of antioxidants found in foods are safe, unless you are juicing a lot of fruits/vegetables daily .

    Resources for Facts About Supplements

    These web sites offer helpful information about medications and supplements:

    • NIH Office of Dietary Supplements .
    • National Center for Complementary and Integrative Health .

    Selenium: Questions And Answers

    Is Collagen Good For Prostate Cancer
    • Vitamin E and selenium.

    Early results of SELECT reported in 2009 found no difference in the rate of prostate cancer among the 4 groups. In the selenium alone group, there was a slight increase in the rate of diabetes mellitus. Even though this change was not clearly shown to be due to the supplement, the men in the study were advised to stop taking the study supplements.

    In 2014, further results of SELECT showed that selenium supplements in men with low selenium levels at the start of the trial had no effect on prostate cancer risk. However, selenium supplements in men who had high levels of selenium at the start of the trial increased the risk of aggressive prostate cancer.

    A study of 1,434 men in SELECT suggested that changes in certain genes which control the way selenium is used by the body may have an effect on the risk of prostate cancer.

    Several factors may have affected study results, including the dose of vitamin E and the form of selenium used. The authors concluded that men should avoid selenium at doses that are higher than the recommended dietary intake.

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    Best Types Of Collagen For Men To Use

    The best types of collagen for men to use really depends on individual preference. Collagen peptides may be sourced from animals such as fish, cows or pigs, and some supplements are produced from multiple sources. Its important to make sure you arent allergic to any of the supplements ingredients.

    Some manufacturers use third party labs to ensure the quality and purity of their products. Choosing a supplement with this added safety check may help avoid contamination. For example, NSF International certifies that the supplement label matches the ingredients and checks for contaminants.

    Always take the time to research any supplement before use. Check with your doctor before taking any collagen supplement to make sure it wont interact with medications or affect any health conditions such as diabetes, high blood pressure or high cholesterol.

    Medically Reviewed

    Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality.

    Drugwatch partners with Physicians Review Network Inc. to enlist specialists. PRN is a nationally recognized leader in providing independent medical reviews.

    Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry.

    What You Need To Know About The Prostate Collagen Supplements & Prostate

    A enlarged prostate can also cause blockages in the urethra. A blocked urethra can also damage the kidneys. A patient suffering from an enlargement of the prostate may have pain in his lower abdomen and genitals. If pain is present, a digital rectal examination will reveal hard areas. A doctor may prescribe surgery or perform an endoscopic procedure. If the enlarged prostate is not completely removed, it will shrink.

    While the size of an enlarged prostate will influence the extent of urinary symptoms, men may experience a range of urinary symptoms. Some men have minimal or no symptoms at all. Some men will have a very enlarged prostate, whereas others will have a mild enlargement. Generally, the symptoms can stabilize over time. Some men may have an enlarged prostate but not notice it. If they have an enlarged colon, their physician can perform a TURP procedure.

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    Summary Of The Evidence For Prostate Cancer Nutrition And Dietary Supplements

    To assist readers in evaluating the results of human studies of integrative, alternative, and complementary therapies for cancer, the strength of the evidence associated with each type of treatment is provided wheneverpossible. To qualify for a level of evidence analysis, a study must:

    Separate levels of evidence scores are assigned to qualifying human studies on the basis of statistical strength of the study design and scientific strength of the treatment outcomes measured. The resulting two scores are then combined to produce an overall score. For an explanation of the scores and additional information about levels of evidence analysis and scores, see Levels of Evidence for Human Studies of Integrative, Alternative, and Complementary Therapies.

    Vitamins Diet Supplements And Cancer

    Prostate Health 2.0

    Vitamins, minerals, essential fats and amino acids are important nutrients for our bodies. Eating a varied amount of these nutrients gives us energy and helps our bodies to grow and repair.


    • Try to eat a balanced diet with plenty of fresh fruit and vegetables.
    • Low levels of nutrients can make you feel ill.
    • Use supplements under the supervision of your medical team and a dietitian.

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    Possible Risks For Men Taking Collagen Supplements

    Collagen supplements are generally considered safe to consume, but they can potentially have risks. Rare collagen supplement side effects are typically mild and may include digestive issues or gas.

    The U.S. Food and Drug Administration regulates collagen supplements as food, which is governed less rigorously than pharmaceuticals, Clinical trials to prove efficacy are not required. Its up to manufacturers to test their products and consumers to properly research the product before use.

    More research is needed on the overall benefits of collagen peptides, but its well-documented that they wont harm you in proper doses. Beth Czerwony, RD Source: Cleveland Clinic

    Potential collagen supplement health risks include allergic reactions and possible supplement contamination from toxins and heavy metals. The FDA has published recalls for undeclared allergens, misbranding and bacterial contamination.

    In 2018, for example, Bulletproof 360 Inc. recalled its collagen protein products because of potential listeria contamination. To check for any recent recalls, visit the FDAs Recalls, Market Withdrawals, & Safety Alerts page.

    Should Collagen Be Part Of Mens Diets

    Collagen can be a part of mens diets, though the benefits of collagen for men or women in supplement form are still being explored. Dieticians recommend eating foods rich in collagen to help support natural collagen production in the body.

    Fish, meat, eggs, poultry, dairy, soy and legumes all contain amino acids that are thought to help produce more collagen. Eating foods rich in zinc, such as whole grains, seeds, nuts and leafy greens as well as foods rich in vitamin C, such as citrus and berries to provide nutrients essential to collagen production.

    If you choose to try a supplement, collagen powders may be mixed into drinks or food and supplements in pill form may be taken with meals. The typical dose of collagen peptides per day is 2.5 to 15 grams, or about one to two scoops of collagen powder.

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    Answer: Use Of Supplements And Collagen After Breast Augmentation

    Thank you for the question. Despite your interest in the use of supplements, I do not think that there is any evidence that supplements or of collagen help or hurt after breast augmentation surgery. On the other hand, I think that you could potentially waste a lot of time, energy, and resources if you were to believe everything you read and/or hear. As far as resuming supplements and/or medications after surgery, patients should follow their plastic surgeons recommendations ultimately he said/she knows exactly how you are progressing and is responsible for your care. Best wishes.

    The Role Of Collagen In Heart Health

    Prostate Take CareTM, 60 Vcaps

    Besides protecting against the spread of cancer, collagen also supports heart health. In fact, according to Linus Pauling, one of the most influential chemists of the 20th century, a shortage of collagen contributes to heart disease, but adequate doses of vitamin C, which promotes collagen production, can help prevent its onset.

    That said, its important to note that too much collagen can raise the risk of heart disease. In one study, researchers found that excessive amounts of collagen end up forming a cement-like mesh around the arteries and blood vessels, which results in poor blood circulation.

    Over time, these encased arteries make it difficult for the heart muscles to contract, increasing the risk of heart failure and organ damage due to high blood pressure.

    Therefore, maintaining healthy collagen levels is crucial for preventing heart failure and other complications that arise due to high blood pressure.

    Collagen is essential for heart health and cancer prevention. To help your body create collagen, eat a balanced diet that contains protein-rich foods like beef, chicken, fish, beans and eggs. You can also increase your consumption of vitamin C-rich foods or take supplements to boost your heart health.

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    What You Need To Know About The Prostate Collagen Supplements And Prostate Cancer

    A enlarged prostate can also cause blockages in the urethra. A blocked urethra can also damage the kidneys. A patient suffering from an enlargement of the prostate may have pain in his lower abdomen and genitals. If pain is present, a digital rectal examination will reveal hard areas. A doctor may prescribe surgery or perform an endoscopic procedure. If the enlarged prostate is not completely removed, it will shrink.

    While the size of an enlarged prostate will influence the extent of urinary symptoms, men may experience a range of urinary symptoms. Some men have minimal or no symptoms at all. Some men will have a very enlarged prostate, whereas others will have a mild enlargement. Generally, the symptoms can stabilize over time. Some men may have an enlarged prostate but not notice it. If they have an enlarged colon, their physician can perform a TURP procedure.

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    Questions To Ask Your Health Care Provider About Cam

    When considering complementary and alternative therapies, patients should ask their health care provider the following questions:

    • What side effects can be expected?
    • What are the risks related to this therapy?
    • What benefits can be expected from this therapy?
    • Do the known benefits outweigh the risks?
    • Will the therapy affect conventional treatment?
    • Is this therapy part of a clinical trial?
    • If so, who is the sponsor of the trial?
    • Will the therapy be covered by health insurance?

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    Heres What The Science Says

    Dietary supplements can help with diagnosed vitamin deficiencies, such as shortages of vitamin D, B6, or B12, which are common among older adults. But what about your prostate?

    Over-the-counter supplements touted to support prostate health are popular, and research has shown that men with a family history of prostate cancer are more likely to take them.

    These pills supposedly help prevent and manage symptoms of an enlarged prostate . Some of the ingredients are said to protect against prostate cancer or slow its growth. But is there any truth to these claims?

    “Research has explored supplements role in prostate health suggesting positive results,” says Dr. Quoc-Dien Trinh, a urological surgeon at Harvard-affiliated Brigham and Womens Hospital. “But the findings are often observational, showing only an association, and are far from conclusive.”

    What Are Some Types Of Collagen Supplements

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    In recent years, collagen has become a popular edible supplement. You can buy it in gelatin, capsule, liquid, fruit chew, or powder form.

    Collagen supplements comes in three types:

    • Gelatin. If you boil collagen for a long time, you end up with gelatin, the most basic form of edible collagen. Thats because the larger proteins found in collagen get broken down into smaller proteins. Collagen is what thickens bone broth.
    • Hydrolyzed collagen. Hydrolyzed collagen is the most common type of collagen supplement sold. In this form, the collagen is broken down into basic amino acids, making it easier for your body to absorb. Hydrolyzed collagen is also known as collagen peptides, collagen hydrolysate, and hydrolyzed gelatin.
    • Undenatured type II collagen . UC-II is not broken down, so its harder for your body to digest and absorb.

    Hydrolyzed collagens dissolve in both hot and cold liquids. You can add them to hot tea or smoothies. Gelatin only dissolves in hot liquid, so its not suitable for cold drinks.

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    Prostate Cancer Nutrition And Dietary Supplements Patient Version

    On This Page

    Complementary and alternative medicine is a form of treatment used in addition to or instead of standard treatments.

    In the United States, about 1 out of every 8 men will be diagnosed with prostate cancer. It is the most second-most common cancer in men in the United States. CAM use among men with prostate cancer is common. Studies of why men with prostate cancer decide to use CAM show that their choice is based on medical history, beliefs about the safety and side effects of CAM compared to standard treatments, and a need to feel in control of their treatment.

    CAM treatments used by men with prostate cancer include certain foods, dietary supplements, herbs, vitamins, and minerals.

    Different types of research have been done to study the use of CAM in prostate cancer. These study types include the following:

    CAM treatments have been studied to see if their use lowers the risk of prostate cancer, kills prostate cancer cells, or lowers the risk that cancer will come back after treatment. Most of these studies used prostate-specific antigen levels to find out whether the treatment worked. This is a weaker measure of how well the treatment works than direct measures, such as fewer new cases of prostate cancer, or smaller tumor size or lower rate of recurrence after treatment for prostate cancer.

    This PDQ summary has sections about the use of specific foods and dietary supplements to prevent or treat prostate cancer:

    Interaction Between Collagen And Tumor Matrix Components

    The complex interactions among collagen and matrix proteins within ECM cells contribute to cancer initiation and progression, as shown in Fig. .

    Fig. 2

    The complexity between collagen and the extracellular matrix. Multiple stromal cells and the extracellular matrix play important roles in stimulating or inhibiting collagen functions via different pathways in cancer progression. Collagen-rich extracellular matrices can bind to other molecules to form dense fibrosis, which induces an anoxic environment and changes the condition of new blood vessels. The behavior of cancer cells is also closely related to collagen. This process also affects the activity and localization of innate and adaptive immune cells

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