Tuesday, November 28, 2023

What Is The Best Prostate Biopsy Procedure

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The Transperineal Prostate Needle Biopsy

Mayo Clinic Minute: New prostate biopsy technique reduces infection risk

Requires a general anaesthetic, so you need to book out the day or even overnight. Remember, as noted above, your perineum is the part of the body between the anus and the scrotum. An incision is made in order to access the prostate for biopsy collection.

Now you know what type of prostate biopsy you might have, what about those seven questions I mentioned before? to see if they have been answered?

How To Get The Most For Your Money

Even if your insurance does cover some or most of your prostate biopsy, youll likely pay a portion of the total cost out-of-pocket. To make sure youre getting the most care for your money:

  • Ask your insurance company about your costs, like co-insurance, copays, and deductibles.

  • Utilize your Health Savings Account , Flexible Spending Account , and Health Reimbursement Account to cover out-of-pocket expenses.

  • Use Amino to compare prices for different doctors.

  • Have a conversation with your doctor. This is especially important if you dont have insurance and are paying for the full cost of the biopsy yourself. Some doctors will offer a discount or an interest-free payment plan if they know youre shouldering the cost on your own.

Prepare For The Immediate Complications

A prostate biopsy usually has the primary complication of bleeding. You can see blood in the urine, in the stool, or in your semen. Also, you may feel pain in your pelvic floor for up to one week. You need to understand before the procedure why this happens. That way, you will be able to tell when the bleeding is too much. Be sure to ask your doctor what to expect in your case.

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What Does My Prostate Do

The prostate is beneath the bladder and in front of the rectum. Itâs a walnut-shaped gland that surrounds part of the urethra. . Hereâs what it does:

  • It produces fluid for semen, which includes sperm produced in the testicles.
  • It prevents urine from being included during ejaculation.

If it gets too big, your prostate can block pee from passing through the urethra and out the penis.

What To Watch For Afterward

prostate biopsy procedure video

Here are the most common complications of prostate biopsy:

  • Pain in the area between the anus and scrotum for a few days to a week.
  • Blood in your urine for a few days to several weeks.
  • Blood in the stool for a day or so. If it lasts longer, notify your physician.
  • Blood in the semen for three to six weeks, and possibly longer.

Make sure to notify your doctor if rectal or urinary bleeding get worse. Also, be on guard in the first 24 to 48 hours for signs of a serious infection in the urinary tract or prostate gland. “The alarm signs are fever or chills,” Dr. Garnick says. “If you experience this, get to a hospital immediately for intravenous antibiotics.” A runaway infection can be dangerous, so don’t ignore the signs.

Another uncommon but dangerous complication is urinary retentionthe inability to pass urine caused by an infection. Seek care immediately if you stop being able to urinate after a biopsy.

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What New Biopsy Techniques Are Out There

Research is developing on other biopsy techniques that use MRIs. In this technique, doctors combine real-time ultrasound imaging with MRI data to guide a biopsy. A recent study published in the Journal of the American Medical Association that concludes using MRI with ultrasound produces better biopsy results1. This method aims to give a more accurate biopsy result while minimizing side effects including infection, bleeding, and potential damage to the urethra or nerves causing temporary incontinence and/or erectile dysfunction.

For men who have had a negative biopsy, there is a new test called ProMark. This helps to predict whether the next biopsy will also be negative, potentially cutting down on the number of biopsies a man will have to go through.

What The Studies Say

In a Finnish survey about prostate biopsies and the need for rebiopsy, 18% of men said they would not accept a new biopsy, and the leading cause was pain. This symptom is sometimes as severe as causing tension and anxiety in men. Many of them end up with an unfavorable attitude to the procedure. Others are adequately treated or maintain close contact with the doctor reporting their symptoms and adjusting the doses. When patients achieve relief, they are more likely to accept a new biopsy if needed in the future.

Pain measurement studies in prostate biopsy use different methods to assess pain. The most common is a scale from 0 to 10, known as the visual analog scale. Other instruments can simply measure the respiratory rate, serum cortisol levels, or blood pressure. According to these studies, when patients feel very anxious, their perception of pain increases. Thus, the more nervous the patient is, the higher the need for anesthesia.

However, most studies mentioned above evaluate pain during the procedure and shortly after. As noted above, feeling pain is natural after any surgical procedure and not an alarming sign at all. Pain should go away after a few days or one week, and it is easier to manage as the days go by. If you still have significant pain symptoms one or two weeks after a prostate biopsy, it will be a good idea to talk to your doctor. You might have a complication -usually an infection- that is not allowing for a complete recovery.

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Is A Prostatebiopsy Painful

A prostate biopsy is a surgical procedure, and what people feel after is very similar to what people feel after surgery. After any surgical procedure and when the anesthesia wears off, people feel pain. They need to use anti-inflammatory drugs to manage their symptoms, and the intensity is variable. You have people who manage their pain efficiently and others who are significantly affected by the symptom. Something similar happens after a prostate biopsy.

Anesthesia is not always used in a transrectal ultrasonography-guided biopsy. So, it might be a good idea to ask your doctor if hes going to use anesthesia or not. Certain studies show that theres no significant difference in pain symptoms with and without anesthesia. Others mention that anesthesia reduces the sensation of pain significantly. Due to diverging studies, anesthesia use is not explicitly written in the protocol, and some doctors prefer not to use it. However, it is essential to achieve adequate pain management in this procedure in any way or another. Ask your doctor what will be the method he will use to manage pain .

What Does A Prostate Biopsy Involve

Prostate biopsy procedure explained by urologist

If you decide to have a biopsy, youll either be given an appointment to come back to the hospital at a later date or offered the biopsy straight away.

Before the biopsy you should tell your doctor or nurse if youre taking any medicines, particularly antibiotics or medicines that thin the blood.

You may be given some antibiotics to take before your biopsy, either as tablets or an injection, to help prevent infection. You might also be given some antibiotic tablets to take at home after your biopsy. Its important to take them all so that they work properly.

A doctor, nurse or radiologist will do the biopsy. There are two main types of biopsy:

  • a trans-rectal ultrasound guided biopsy, where the needle goes through the wall of the back passage
  • a transperineal biopsy, where the needle goes through the skin between the testicles and the back passage .

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Biopsy During Surgery To Treat Prostate Cancer

If there is more than a very small chance that the cancer might have spread , the surgeon may remove lymph nodes in the pelvis during the same operation as the removal of the prostate, which is known as a radical prostatectomy .

The lymph nodes and the prostate are then sent to the lab to be looked at. The lab results are usually available several days after surgery.

What Happens After A Biopsy

A negative biopsy indicates that none of the biopsy samples found any evidence of prostate cancer. This is usually good newshowever, this does not necessarily mean that there is no prostate cancer present. Your doctor may want to continue to monitor your PSA levels or do a repeat biopsy at some point in the future.

A positive biopsy indicates that there is evidence of prostate cancer. This would be considered a diagnosis of prostate cancer. At this point, you should also have some idea of the approximate location, size, and aggressiveness of the cancer. What happens next is a decision between you and your doctor. There are some additional tests you can take to give you a better idea of your diagnosis. For example, genomic tests can help provide information on how likely your cancer is to spread, or how aggressive it is likely to be.

In addition, there are additional new tests that can be performed with a biopsy to help make diagnosis and determine the aggressiveness of the cancer:

  • ERG Protein Marker
  • A marker used on prostate tissue after a biopsy, which measures ERG protein assays. This helps doctors identify patients who have the disease or have pre-cancerous lesions that indicate a patient is more likely to develop prostate cancer over time.
  • SelectMDx
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    Talk With Your Healthcare Provider

    Tell your healthcare provider if you:

    • Take anticoagulants . These are medications that affect the way your blood clots.
    • Take steroids, such as prednisone .
    • Take any other medications, including vitamin E, multivitamins, herbal remedies, or any other dietary supplements or home remedies.
    • Have taken any antibiotics in the past 3 months.

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    Siu Medicines Experience With Mri/us Fusion Technology:


    The development of the fusion of MRI images and ultrasound images has revolutionised biopsy procedures. Thanks to fusion technology, the urologist is now able to:

    • Detect potential cancer sites before carrying out the biopsy thanks to MRI test
    • Locate suspect areas on the ultrasound image in real time during the biopsy
    • Guide the biopsy needle directly into the suspect areas on the MRI
    • Record the position of the biopsies performed in 3D prostate mapping
    • All with the precision of a few millimetres

    Result: A detailed diagnosis leading to personalised patient care.

    Example of Fusion biopsy procedure:

    1. Radiologist defines suspicious lesion on the MRI
    2. MRI and 3D Ultrasound Image Fusion
    3. Targeted Biopsy

    Further information about fusion biopsies

    Despite its performance and the clinically proven benefits, prostate fusion biopsy is still not the most common practice. The main reasons for which it is not yet widespread are the acquisition cost, the need for access to an MRI scanner, and the novelty of the technology.

    Locate a urologist or a clinic on the Koelis® Solution Locator.

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    What Can You Expect During A Prostate Ultrasound And Biopsy

    The procedure is short and generally only takes about 10 minutes. Your urologist, a doctor specializing in mens genital and urinary problems, will perform the procedure.

    • Upon arrival in the examination room, you will be given antibiotics to prevent infection.
    • You will be asked to lie on your side and bring your knees to your chest.
    • The area being tested may be numbed to help reduce any discomfort.
    • A lubricated probe is inserted into the rectum to generate the ultrasound.
    • A small needle is inserted through the probe to take several tiny tissue samples from the prostate. Some men may feel mild pressure or discomfort during the procedure.
    • After tissue samples are taken, they are sent to a lab for an analysis.

    Benefits Of Getting A Prostate Biopsy

    A prostate biopsy is the only way to definitively determine whether you have prostate cancer and, if you do, how aggressive it is.

    While prostate biopsies arent always conclusive, in general, a biopsy gives men the reassurance of knowing whether they have cancer or not. If you know you have prostate cancer, youre more likely to be appropriately treated.

    Appropriate prostate cancer treatment options depend on several factors, including the stage of the cancer, your age, your general health and which risk category your cancer falls into.

    Localized prostate cancer is categorized into six risk categories, which range from very low-risk to very high-risk. The risk group is determined by the stage of your cancer, your PSA levels and the Gleason score obtained from the biopsy pathology report.

    The National Comprehensive Cancer Network guidelines outline appropriate treatment options based on risk categories and whether the cancer has already metastasized.

    Patients whose cancer is confined to the prostate and falls into the very low-risk and low-risk categories tend to have slow-growing cancers. Treatment options for these patients often include active surveillance, radiation therapy or surgery. Similar treatment options may be recommended to patients in the low-risk and favorable intermediate prostate cancer risk categories.

    The NCCN guidelines recommend immediate treatment for patients with high-risk disease or those patients whose cancer has metastasized.

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    Targeted Prostate Biopsy: What You Should Know

    Targeted biopsy is being used at UCLA to diagnose prostate cancer. Targeted biopsy refers to using advanced imaging techniques to identify areas of the prostate suspicious for cancer, and then directly biopsying them. The traditional method of biopsy uses ultrasound imaging, with which tumors are hard to see. With targeted prostate biopsy, systematic sampling of prostate tissue is performed. The new method employs sophisticated MRI technology, developed at UCLA, to visualize prostate cancer, and fusion of the MR images with real-time ultrasound using the specialized biopsy equipment. The result is a 10-20-minute procedure, done in the clinic under local anesthesia, that is much more accurate at finding significant prostate cancer in men.

    Positron Emission Tomography Scan

    What you need to know in preparation for Prostate Biopsy

    A PET scan is similar to a bone scan, in that a slightly radioactive substance is injected into the blood, which can then be detected with a special camera. But PET scans use different tracers that collect mainly in cancer cells. The most common tracer for standard PET scans is FDG, which is a type of sugar. Unfortunately, this type of PET scan isnt very useful in finding prostate cancer cells in the body.

    However, newer tracers, such as fluciclovine F18, sodium fluoride F18, and choline C11, have been found to be better at detecting prostate cancer cells.

    Other newer tracers, such as Ga 68 PSMA-11 and 18F-DCFPyl , attach to prostate-specific membrane antigen , a protein that is often found in large amounts on prostate cancer cells. Tests using these types of tracers are sometimes referred to as PSMA PET scans.

    These newer types of PET scans are most often used if its not clear if prostate cancer has spread. For example, one of these tests might be done if the results of a bone scan arent clear, or if a man has a rising PSA level after initial treatment but its not clear where the cancer is in the body.

    The pictures from a PET scan arent as detailed as MRI or CT scan images, but they can often show areas of cancer anywhere in the body. Some machines can do a PET scan and either an MRI or a CT scan at the same time, which can give more detail about areas that show up on the PET scan.

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    How Should You Prepare For A Prostate Ultrasound And Biopsy

    Preparation for a prostate ultrasound and biopsy is simple. You shouldnt take any blood-thinning medications such as warfarin , clopidogrel , aspirin or ibuprofen before a prostate biopsy because blood thinner increase the risk of bleeding. If you are already taking blood thinners, your doctor will discuss with you how many days prior to the biopsy they should be held.

    Most healthcare providers dont ask you to follow any type of special diet before a biopsy. However, they suggest eating lightly before the procedure and drinking only clear liquids. Check with your providers office to see if you need to do anything additional to prepare for the test.

    What Is A Transperineal Biopsy

    This test is a needle biopsy to look for cancer cells in the prostate. Your doctor puts a needle into the prostate through the skin behind the testicles . They take a number of samples, which are sent to the lab to be looked at under a microscope.

    This type of procedure can sometimes find a prostate cancer that has been missed by other types of biopsy.

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    How Do You Prepare For A Prostatebiopsy

    If you were ordered a prostate biopsy, its because your doctor examined your case and determined that youre a candidate. He has probably told you what it is about, which method hes going to use, and how it will be like. But if you havent discussed everything with your doctor, that is one of the first things on your list. Talk to your doctor and ask him any question you have. Every one of us has different traits and risk factors. You may need specific advice according to your case.

    You will probably undergo these preparation steps before a prostate biopsy:

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    Other Types Of Prostate Biopsies

    Procedure for Mapping Biopsy of the Prostate

    While the transrectal prostate biopsy is the most common, there are other types of biopsies that your urologist may perform.

    Transperineal biopsy

    Done under local or general anesthesia, this biopsy takes prostate samples by inserting a needle through the skin of the perineum . As this procedure allows a larger area of tissue to be examined than a transrectal biopsy, your urologist may order one if they think you have cancer despite a negative transrectal biopsy.

    Transurethral biopsy

    Done under local or general anesthesia, this biopsy goes through the urethra to collect the prostate samples. To do this, the urologist inserts a thin tube with a camera attached into the penis. A surgical tube is then passed through the cystoscope to collect the samples.

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