Eight Types Of Standard Treatment Are Used:
Watchful waiting or active surveillance
Watchful waiting and active surveillance are treatments used for older men who do not have signs or symptoms or have other medical conditions and for men whose prostate cancer is found during a screening test.
Active surveillance is closely following a patient’s condition without giving any treatment unless there are changes in test results. It is used to find early signs that the condition is getting worse. In active surveillance, patients are given certain exams and tests, including digital rectal exam, PSA test, transrectal ultrasound, and transrectal needle biopsy, to check if the cancer is growing. When the cancer begins to grow, treatment is given to cure the cancer.
Other terms that are used to describe not giving treatment to cure prostate cancer right after diagnosis are observation, watch and wait, and expectant management.
Focal Ablative Salvage Therapy
More recently, there is a growing body of research on focal salvage therapy to target just the identified tumor. This approach is called Focal Ablative Salvage Therapy, or FAST. Thanks to mpMRI and MRI targeted biopsy, the tumors location, extent, aggressiveness and genomics can be identified. Ablating just the tumor offers the dual advantage of cancer control plus low side effect risks. As with whole-gland primary treatment, the same three ablation methods can be used.
As of this writing, the most recent data was presented at the 2022 annual meeting of the American Urological Association by Dr. Deepika Reddy . The statistics were drawn from 288 consecutive cases of radiation recurrence that were treated with either focal HIFU or focal cryo . According to Dr. Reddys presentation, 265 patients had pertinent follow-up records for analysis. Patients had either stage T2 or T3 disease, and Grade Group 2, 3 or > 3.
Treatment was deemed successful based on failure-free survival and retreatment-free survival . The numbers are very encouraging, with 77% success rates for both FFS and RFS at 6 years post-FAST. About 7% of patients had adverse events following ablation, most of which were urinary infections. These patients avoided the surgical trauma of salvage prostatectomy, the increased cancer risk of salvage radiation, and the likely side effects of both.
What About People Visiting
If you are sick or have been exposed to COVID-19, we ask that you not come to Beverly Hills Cancer Center. We ask that you find someone who isnt sick to join your loved one at their appointments.
To protect all patients, we may limit the number of people who can visit someone staying in the hospital. Please check with your care team.
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Community Prostate Cancer Screenings
Northside Hospital Cancer Institute holds multiple prostate cancer screenings for community members each year at several convenient locations throughout Georgia.
Men who meet the following criteria are eligible to register and attend NHCI community prostate cancer screenings:
- Men who are between the ages of 45-75
- Men who do not have a prostate cancer diagnosis
- Men who have not had a PSA blood test within the past year
To register for an upcoming Northside Hospital community prostate cancer screening, please call . Qualified interpreters are available to assist you at each screening event. Please inform registration staff members of your language preference.View upcoming dates for our prostate cancer screening events on our Classes & Event Calendar.
Men are encouraged to make an informed decision with their health care provider regarding the appropriateness of prostate cancer screening.
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Mayo Clinic Rochester Ny
A non-profit organization that values education, research, and whole-person care to their patients from five different states and almost 140 countries. Mayo Clinics International patient offices supply the opportunity for patients around the globe to experience the top-tier Mayo Clinic care.
Doubling as an education and biomedical research center, the Johns Hopkins Hospital has over 40 locations and treats almost 4 million patients each year. Their Sidney Kimmel Comprehensive Cancer Center treats 25 types of cancers with carefully tailored treatment.
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Dealing With Treatment Side Effects
Pelvic Muscle Exercises
Pelvic muscle exercises, also known as kegels, are an essential part of improving incontinence and preventing it from worsening. Learn more.
Erectile dysfunction affects millions of men and occurs for a range of reasons, but there are also many treatments that allow you to continue a satisfying sexual life.
Why Choose Md Anderson For Your Prostate Cancer Treatment
Choosing the right hospital may be the most important decision you make as a prostate cancer patient. At MD Anderson youll get care and support from one of the nations top-ranked cancer centers.
Here, you can benefit from the expertise at our Multidisciplinary Prostate Clinic. Most newly diagnosed patients with intermediate to high-risk prostate cancer have a choice between surgery or radiation therapy. During your first clinic visit you will have a joint appointment with a radiation oncologist and surgeon who both specialize in prostate cancer. The three of you will review your case and discuss your treatment options. Your doctors may even discuss clinical trials with you, which could offer better outcomes than standard treatments.
If you have a more complex cancer, such as a disease that has recurred or spread, we offer the most advanced therapies. Thanks to our robust research and clinical trial programs, these may include new surgical options or new cancer drugs, such as targeted therapy or immunotherapy.
Finally, all patients can benefit from the services MD Anderson offers as a comprehensive cancer center. These include social work counseling, nutrition and exercise guidance, psychiatric support and care for health problems that may be impacted by your cancer, such as diabetes and arthritis.
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When Is Brachytherapy Alone The Right Choice
For some patients with disease that is confined to the prostate and not too aggressive , brachytherapy alone is a good option. It is also convenient for the patient as it is done in an outpatient setting and most people can get back to work within a few days.
But brachytherapy is not right for everyone. For some patients with less-aggressive disease, a watch-and-wait approach would be preferred. At MSK, our philosophy is that when the disease is caught very early, it is very appropriate to do active surveillance and hold off on treatment.
This philosophy applies to patients with a low PSA level, or nonaggressive disease as reflected by a Gleason score of 6 with evidence of cancer in only a few of the biopsy samples and no evidence from the MRI of a significant amount of disease. There are also very select patients with Gleason 7 disease who may be candidates for active surveillance.
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Smilow Comprehensive Prostate Cancer Center
Where to Find Us
222 East 41st Street, 12th FloorNew York,NY10017
We combine competence with compassion to give you the personalized prostate cancer treatment you need.
When youve been diagnosed with prostate cancer, we understand that you have many decisions to make: which type of treatment should you choose? How aggressive should the treatment be? And whom should you trust with your care?
At NYU Langones Smilow Comprehensive Prostate Cancer Center, part of NYU Langones Perlmutter Cancer Center, we use personalized care coupled with evidenced-based medicine to identify which patients can benefit from aggressive treatment and those who can safely pursue a more conservative approach.
Our excellence in surgery, treatment outcomes, and imaging has made us one of the leading prostate cancer care centers in the country. Our nerve-sparing surgery techniques have revolutionized prostate cancer care and ended the days when men had to choose between fighting cancer and preserving their sexual function.
We offer the most up-to-date programs in prostate cancer screening and detection, which allows us to accurately assess your cancer risk and guide treatment recommendations. Our radiologists and urologists pioneered the use of MRI to identify areas of potentially aggressive disease so we can target biopsies. In addition, we are continually researching ways to improve prostate cancer screening and detection.
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These Technologies Could Change Your Life For The Better
The da Vinci® Surgical Robot assists with laparoscopic prostatectomies and represents the most advanced prostate cancer treatment available today. The da Vinci® provides superior 3D visualization, as surgeons use its robotic arms to perform prostate surgeries through keyhole sized incisions. The actual surgical instruments are the size of match heads, ensuring precise control that results in:
What Lies Ahead: Leading The Way With Alpha Therapies
The coming years will see even more powerful forms of radioactive therapy. The MSK laboratory of radiochemist Jason Lewis and other researchers are investigating the use of alpha particles, which have a much higher energy hundreds of times more potent than the photons used in conventional radiation or beta particles. Not only do alpha particles cause more damage when they slam into cancer cells but their path of destruction is more tightly focused, sparing normal cells.
MSK is building one of the nations first dedicated alpha particle GMP labs at a U.S. academic institution.
These radiopharmaceuticals that we are creating translate very well from bench to bedside, says Dr. Lewis, Chief of the Radiochemistry and Imaging Sciences Service and Director of the Radiochemistry and Molecular Imaging Probe Core Facility. When you see these striking responses to treatment, it brings real hope for the future and our patients.
Advances in radiotheranostics are supported by The Tow Foundation, long-time contributors to MSKs mission.
- A new FDA-approved drug could be an effective treatment against prostate cancer that has spread.
- The treatment uses a molecule that seeks out and attaches to a specific protein on the cancer cell surface called PSMA
- The technology delivers radiation that damages DNA and destroys the cancer cell..
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Lower Urinary Tract Symptoms
- Abdominal and pelvic CT scan
After taking a detailed medical history and performing a physical examination, including a digital rectal examination, a PSA blood test will be performed. If the PSA level is elevated, a prostate biopsy will be recommended. The biopsy is an outpatient procedure that is performed with local anesthesia. Several samples of tissue are obtained from the prostate. These samples are what tell us if you have prostate cancer. If the biopsy is positive, other tests may be performed based on your PSA level, cancer grade and findings on exam. Most commonly, a CT scan of the abdomen and pelvis will be obtained for clinical staging. In high-risk cases, a bone scan may be recommended to determine if there has been spread to the bones.
The overwhelming majority of prostate cancers are adenocarcinomas, which arises from the glandular component of the prostate. Other rare and atypical types of prostate cancer include:
- Ductal carcinoma
- Clear cell adenocarcinoma
- Giant cell carcinoma
These rare and atypical variants often act aggressively and may respond differently to therapy than the more common prostate adenocarcinoma. As they are rare, however, most men are unaffected by these atypical variants.
Princess Margaret Cancer Centre University Health Network
Toronto, ON, Canada
WebsiteFirst and foremost, the Princess Margaret Cancer Centre, University Health Network is BIG. The institution employs 3,000 staff members and houses 130 beds, 17 radiation treatment rooms, and hundreds of thousands of patient visits every year. Princess Margaret also employs nearly 60 surgical oncologists in one of the most comprehensive surgical cancer care programs in Canada, and the department is always innovating recently developed treatment options include radio-guided seed localization for intra-operative localization of breast cancers, robotic surgery procedures for prostate cancer, and a specialized program for peritoneal cancers. As one of the best cancer hospitals in Canada, Princess Margaret also offers Gamma Knife Â® surgery and a Plastic and Reconstructive Surgery department.
High Tech Specs: Stem cell research, Cell signaling, Genomics, Protemics, Bioinformatics
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Cancer May Spread From Where It Began To Other Parts Of The Body
- Lymph system. The cancer gets into the lymph system, travels through the lymph vessels, and forms a tumor in another part of the body.
- Blood. The cancer gets into the blood, travels through the blood vessels, and forms a tumor in another part of the body.
The metastatic tumor is the same type of cancer as the primary tumor. For example, if prostate cancer spreads to the bone, the cancer cells in the bone are actually prostate cancer cells. The disease is metastatic prostate cancer, not bone cancer.
There Are Three Ways That Cancer Spreads In The Body
- Tissue. The cancer spreads from where it began by growing into nearby areas.
- Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.
- Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body.
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The Best Care For Prostate Cancer
When it comes to prostate cancer, there are no easy answers. We strive make it easier. We confirm a prostate diagnosis, even when prostate cancer is hard to find because the tumors are very small. We are experts at diagnosing these challenging cases.
Our specialized team develops a personalized treatment plan for you that aims to preserve your urinary and sexual function. We explore all minimally invasive options, including active monitoring before recommending surgical removal of your prostate or external radiation therapy. We offer minimally invasive treatments such as cryosurgery a type of focal therapy that targets a section of the prostate gland containing the cancer rather than the whole prostate and high-dose brachytherapy radiation, which kills cancer cells in your prostate while potentially preserving healthy tissue.
We are also strong advocates of active surveillance or watchful waiting for small, nonaggressive prostate cancer. We believe active surveillance is a safe and important course for certain men with prostate cancer who may be candidates to avoid treatment altogether.
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What Are The Side Effects Of Brachytherapy
- Frequent urination or urinary retention or burning with urination
- Erectile dysfunction
- Urethral stricture or narrowing of the urethra
- Diarrhea or blood in the stool
- Secondary cancers
For the short time that the seeds are giving off larger amounts of radiation, you should avoid close proximity to children or pregnant women. Make sure to talk with your radiation oncologist or oncology nurse for instruction about radiation safety and exposure for family members or pets.
If you are traveling through an airport following brachytherapy treatment, there is a chance that radiation detectors will be set off. Talk to your radiation oncologist and ask for a note to indicate youve just had radiation treatment.
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Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center is a non-profit hospital located in New York City. It was founded in 1884 as the New York Cancer Hospital by a group of philanthropists and businessmen including John Jacob Astor.
The center treats hundreds of subtypes of cancers each year at its many locations in New York state and New Jersey. These include the Evelyn H. Lauder Breast Center, the Sillerman Center for Rehabilitation, and the Bendheim Integrative Medicine Center.
Prostate Cancer: Why Choose Johns Hopkins
- The Brady Urological Institute and the Johns Hopkins Kimmel Cancer Center take a team-based approach to care, meeting with newly diagnosed patients in a single room, on a single day, for a comprehensive evaluation and consultation.
- As a Precision Medicine Center of Excellence for Prostate Cancer, our team uses precision medicine technology to provide the right level of management for each patient leading to better outcomes and a higher value of overall care.
- Our urologic surgeons have extensive experience performing robotic-assisted radical laparoscopic prostatectomies , including nerve-sparing techniques. These procedures provide patients with less pain, a shorter hospital stay and an earlier return to daily activities.
- Our surgeons, oncologists and radiologists are also world leaders in prostate cancer research, giving patients access to the latest discoveries and clinical trial opportunities.
Prostate Cancer | Q& A
Mohamad Allaf, M.D., answers questions about prostate cancer diagnosis and treatment options and discusses robotic prostatectomy at Johns Hopkins.
Recovery from Prostate Cancer | Bills Story
This championship swimmer sought a second opinion at Johns Hopkins. Four weeks after a radical prostatectomy for prostate cancer, he was back in the pool.
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Treatment By Stage Of Prostate Cancer
Different treatments may be recommended for each stage of prostate cancer. Your doctor will work with you to develop a specific treatment plan based on the cancers stage and other factors. Detailed descriptions of each type of treatment are provided earlier on this same page. Clinical trials may also be a treatment option for each stage.
Early-stage prostate cancer
Early-stage prostate cancer usually grows very slowly and may take years to cause any symptoms or other health problems, if it ever does at all. As a result, active surveillance or watchful waiting may be recommended. Radiation therapy or surgery may also be suggested, as well as treatment in clinical trials. For those with a higher Gleason score, the cancer may be faster growing, so radical prostatectomy and radiation therapy are often recommended. Your doctor will consider your age and general health before recommending a treatment plan.
ASCO, the American Urological Association, American Society of Radiation Oncology, and the Society of Urologic Oncology recommend that patients with high-risk early-stage prostate cancer that has not spread to other areas of the body should receive radical prostatectomy or radiation therapy with hormonal therapy as standard treatment options.
Locally advanced prostate cancer
Watchful waiting may be considered for older adults who are not expected to live for a long time and whose cancer is not causing symptoms or for those who have another, more serious illness.