May Lower Blood Pressure
High blood pressure is a huge health risk worldwide. In fact, over 40% of adults over 25 have high blood pressure .
Interestingly, animal studies have shown that the capsaicin in cayenne peppers may reduce high blood pressure.
One study in mice with high blood pressure showed that the long-term consumption of dietary spices containing capsaicin helped reduce blood pressure .
Another study showed that capsaicin helped relax blood vessels in pigs, leading to lower blood pressure .
Its important to note that the findings above are based on animals, and capsaicins effects may differ in humans. It is best to take these findings with a grain of salt.
Capsaicin has appeared to reduce blood pressure in animal studies. Human studies are needed before making a recommendation.
Capsaicin And The Cell Cycle
Cells proliferate through the cell cycle, which is divided into G0/G1, S and G2/M phases, and which has DNA checkpoints to ensure the integrity of DNA replication. The checkpoint and repair pathways facilitate cellular responses to DNA damage. Any alteration in these pathways can increase the risk of cancer. The cell cycle and growth arrest has gained much attention as a defense mechanism against cancer and target for cancer prevention and therapy, as well as tissue homeostasis . Essential parts of the cell-cycle machinery are the cyclins, cyclin-dependent kinases and the CDK inhibitors. Once activated, the CDKs provide a driving force for the cells to move from one phase to the next. In particular, the CDKs and cyclins are highly activated in most cancer types. Therefore, suppression of CDK activity results in cell-cycle arrest and has been identified as a target for cancer therapy to prevent uncontrolled proliferation of cancer cells.
What About Potential Benefits
At the same time, claims have been lodged on behalf of black pepper’s potentially positive impact on health.
For example, the Anesthesia and Uncommon Diseases book also notes that black pepper has been variously used to treat bronchitis, an upset stomach, skin irritation, neuralgia and cancer.
In addition, according to a research published in Critical Reviews in Food Science and Nutrition in June 2013, black pepper which also goes by the scientific name Piper nigrum L. is thought by some experts to have some antioxidant, anti-inflammatory and anti-microbial properties. The study also highlights other claims that black pepper might have potential as an inhibitor of tumor growth and as a means by which to improve gastrointestinal function.
But the study notes that, once again, all the evidence to back up these purported claims is rooted in animal research, which doesn’t necessarily translate to human experience. The study notes that more research involving human participants is needed to confirm such potential benefits.
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May Aid Digestive Health
Dietary spices and their active components may provide many benefits for your stomach.
For example, cayenne pepper may help boost the stomachs defense against infections, increase digestive fluid production and help deliver enzymes to the stomach, aiding digestion (
- Pain after surgery
- Pain from nerve conditions like shingles
Additionally, its important to note that capsaicin cream should not be applied to an open wound or broken skin.
Capsaicin has powerful pain relief properties. It relieves pain by reducing the amount of substance P that your body produces.
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Al Bataina, B. A., Maslat, A. O., and Al Kofahil, M. M. Element analysis and biological studies on ten oriental spices using XRF and Ames test. J Trace Elem.Med Biol. 2003 17:85-90. View abstract.
Amer, A. and Mehlhorn, H. Larvicidal effects of various essential oils against Aedes, Anopheles, and Culex larvae . Parasitol.Res. 2006 99:466-472. View abstract.
Amer, A. and Mehlhorn, H. Persistency of larvicidal effects of plant oil extracts under different storage conditions. Parasitol.Res. 2006 99:473-477. View abstract.
Chaubey, M. K. Fumigant toxicity of essential oils from some common spices against pulse beetle, Callosobruchus chinensis . J Oleo.Sci 2008 57:171-179. View abstract.
Chaudhry, N. M. and Tariq, P. Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates. Pak.J Pharm Sci 2006 19:214-218. View abstract.
Dearlove, R. P., Greenspan, P., Hartle, D. K., Swanson, R. B., and Hargrove, J. L. Inhibition of protein glycation by extracts of culinary herbs and spices. J Med Food 2008 11:275-281. View abstract.
Farag, S. E. and Abo-Zeid, M. Degradation of the natural mutagenic compound safrole in spices by cooking and irradiation. Nahrung 1997 41:359-361. View abstract.
Hasegawa, G. R. Proposals for chemical weapons during the American Civil War. Mil.Med. 2008 173:499-506. View abstract.
65 Navarro, I. T., Vidotto, O., Giraldi, N., and Mitsuka, R. . Bol.Oficina Sanit.Panam. 1992 112:138-143. View abstract.
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How Pepper Fruit Others Stop Prostate Cancer
Chukwuma Muanya, Assistant Editor
*Ameliorate liver, kidney damage caused by multiple exposures to toxic substancesResearchers have identified and validated pepper fruit, pawpaw, West African Black pepper and cowhage for the prevention and treatment of prostate cancer.
Botanically called Dennettia tripetala, pepper fruit belongs to the plant family Annonaceae. It is called Ako in Edo, Nkarika in Ibibio, Mmimi in Igbo, and Ata igbere in Yoruba.
Piper guineense is commonly called West African Black Pepper or Ashanti pepper . Velvet bean or Cowhage is botanically called Mucuna pruriens, Werepe in Yoruba and Agbala in Ibo. Pawpaw is botanically called Carica papaya.
Besides its novel use in prevention and treatment of glaucoma, osteoarthritis, food poisoning, indigestion, and heartburn, among many other disease indications, a recent report from the University of Illinois at Chicago, United States , showed that pepper fruit extract inhibits the growth of prostate cancer cells.
The study is titled Effects of Seed Extracts from Traditional Nigerian Medical Plants on Prostate Cancer Cell Growth.
The study was part of Stephen W. Jagla thesis for the degree of Master of Science in Pathology in the Graduate College of the University of Illinois at Chicago, US, in 2013.
The study was cited in the journal Medical Sciences. It is titled, A Review of the Uses and Medicinal Properties of Dennettia tripetala .
Article #: Black Pepper Causes Cancer
Confirmation of Life Sciences teaching that anything taken into the body that is not a food is poisonous and harmful comes from the research laboratory of the University of Kentucky.
Life Science teaches not to use condiments on, in or with our foodsor by themselves. In fact, we teach to eat only foods that are a gustatory delight in themselves. For good health we must eat only those foods that dont call for the addition of seasonings or spices of any sort. Foods and so-called foods that have to be jazzed up with condiments are unhealthful.
When black pepper was given to mice at the University of Kentucky, they developed problems aplenty, including cancer of the liver, lungs and skin. This is a prime example of how toxic condiments really are. Cayenne pepper, chili powder, salt, basil, cumin seed, caraway, vinegar, garlic and hundreds of other condiments are likewise pathogenic and carcinogenic.
To attain and maintain health, you need to drop condiments from your lifeforever. Eat only fresh raw succulent fruits, vegetables, nuts, seeds and sprouts. The better your diet, the better youll look and feel.
Reprinted from Health Crusader April 1980
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Your Best Prostate Cancer Fighter
Prostate cancer is the most common form of cancer among men. Over 30,000 men die from it in the United States each year. Deaths from prostate cancer failed to drop in past decades while we spent billions on treatments. Heres why: Advanced prostate cancer cells hardly respond even to high doses of drugs or radiation.
Because of the poor response to drugs, scientists keep searching for treatments. Theres particular interest in the compounds found in foods. And capsaicin is one of the best anti-cancer foods there is. But what makes them so powerful?
Cells turn into cancer for one reason they dont die. Normally, cells live their life, replicate, and then they die before they cause any damage. Cancer occurs when the cells refuse to die off. And since peppers help with apoptosis, this gave researchers a clue in discovering why they work so well. They found that capsaicin does something very unique with cancer cells. The hot spice doesnt actually attack the cancer and kill it.
Instead, capsaicin travels through your body looking for cancer cells. When it finds one, it attaches itself to the edge of the cell. From this position on the cell membrane, it switches on a cell receptor called TRPV1. This receptor acts as a channel that determines what goes in and out of the cells.
When the capsaicin turns on the TRPV1, it sends the cancer cell into overdrive where it starts to self-destruct. The more capsaicin in your body, the more cancer cells it forces to self-destruct.
Black Pepper For Digestion
Piperine in black pepper helps to produce more of hydrochloric acid in the stomach which helps to improve digestion. Black pepper has a good amount of potassium and hence it makes the digestive system very strong. Adding some amount of black pepper to a glass of buttermilk will help to get rid of constipation. Constipation is the hardening of stool which makes it difficult for defecting. Consuming black pepper regularly can also prevent diarrhea. Diarrhea is the condition in which the stool becomes too liquid and watery.
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Can Hot Peppers Cure Prostate Cancer
Every year, over 200,000 men in the world lose their battle with prostate cancer, and more are diagnosed with the disease every year. Naturally, we look for anything promising that might cure prostate cancer or prevent it, and in 2006 a few studies on the benefit of the chemical capsaicin, which is found in hot red peppers, suggest we may have found a way to treat more people with prostate cancer and benign prostate enlargement.
According to a joint US/Japan study in mice, mice that had prostate tumors and receive high doses of capsaicin, had about an 80% rate of cell death or apoptosis of tumor tissue. Though researchers note that induced human cancers in mice are easier to treat, this is still a fairly noteworthy result. You can see from the study that capsaicin does not totally cure prostate cancer, but its use may be indicated to prevent tumor growth and as an auxiliary treatment for men who have been diagnosed with prostate cancer. It also appears that some men are aided by the anti-inflammatory properties of capsaicin, which might minimize discomfort and reduce growth of the prostate.
Black Pepper For Kidneys
Is black pepper bad for kidneys? Yes, Black pepper can be very harmful to the kidney. Having too much of it directly without mixing in food can cause kidney damage. People suffering from kidney problems should cut down on the amount of black pepper in their diet. People who are under medication for kidney stone must also take advice of the doctor before including black pepper in your daily diet.
After knowing all the side effects of black pepper you may now ask Is black pepper bad for you? Not really. Black pepper when taken in moderate quantity will only be a boon and not a bane at all. Have a control of the quantity and the way you consume it to get all the benefits of black pepper.
Now that we have spoken about a moderate amount, you may ask how much black pepper is good to take per day. You must keep it in mind that pepper is a spice and hence it cant be taken in a large quantity as a meal. Until and unless you dont take close to a pound of it, it cannot be called too much.
Some amount of it as a seasoning will not do any harm. Even a tablespoon of black pepper once in a while is sure to be beneficial. It is always better to take natural medicines than chemical ones. When one single spice can give so many benefits then why not make it a part of your diet and enjoy good health?
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Black Pepper On Skin Of Children
If is not assured whether children too can get the same benefits on their skin as adults by using black pepper. Black pepper has a lot of heat and might not be beneficial for tender skins of children. Being a spice it may cause redness and burning if they get into the eyes. Hence it is better to avoid black pepper on the face of children.
Herbs And Spices For Cancer Prevention
From pepper to garlic to ginger some favorite ways to pep up your food may also protect you from cancer.
Most chefs and foodies agree that adding a dash of this or pinch of that can transform an ordinary dish into pure magic. But what many culinary experts may not know is the zing that makes your supper sing can also help to prevent cancer. Scientists have found that certain foods, including some herbs and spices, contain phytochemicals, which can affect our bodies biologically. Through their ability to stimulate the immune system, phytochemicals may aid in keeping cancer at bay. Here are six ways to spice up your food and keep you in good health. Now, please pass the pepper!
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High Performance Liquid Cromatography
The experiment was carried out in a high efficiency liquid chromatograph of the Shimadzu-LC20AD brand with photodiode array detection , Kromasil 100-5C18 column , SPD-M20A detector at 345 nm wavelength and 1 mL/minute constant flow. Piperine sample was diluted in acetonitrile. Automatic injection programming was performed so that the injected sample volume corresponded to 20 L. Mobile phases used were: 60% acetonitrile and 40% water in the isocratic method. The running time was 15 min. The retention time band 7.15 min corresponded to the major compound, displaying an area of 98.79% . We can infer that piperine purity is 98.79%.
How Turmeric May Work
The popular herbal medicine contains the antioxidant curcumin, a curcuminoid that is responsible for turmerics yellow color and prevents inflammation by blocking molecules that cause it. Although the medicinal use of turmeric is not fully understood, the spice is commonly used in Ayurvedic medicine to treat a variety of illnesses.
Curcumin, the primary active ingredient in turmeric, protects the body in two ways:
- Enhancing the activity of an important detoxifying enzyme
- Neutralizing molecules that cause DNA damage, such as free radicals
Studies of turmeric in rats have shown the spice to be vital in the prevention of kidney damage from toxins. Additional studies have shown that it may also have protective effects against colon, stomach, and skin cancer by stopping the replication of tumor cells in the lab. The effect in the human body is still being studied.
Although research on turmeric as an anti-cancer supplement has been promising, especially in preventing and limiting the spread of prostate cancer, recent experiments suggest that it may interfere with the activity of some chemotherapy drugs.
Therefore, questions remain about its overall efficacy and clinical relevance as an adjunct to traditional cancer treatments.
Spicy Spin On Treating Prostate Cancer
Capsaicin in Hot Peppers May Prove Useful, Lab Tests Show
March 15, 2006 A natural chemical in hot peppers may become a tool in treating prostate cancer.
The chemical is called capsaicin. It puts the kick in jalapenos, habaneros, and other hot peppers.
A study in Cancer Research shows that capsaicin thwarted prostate cancer cells in lab tests. Capsaicin prompted cancer cells to die and curbed tumor growth, the study shows.
However, capsaicin wasnt tested on people. The experiments were done on prostate cancer cells, including those injected into mice.
The researchers included H. Phillip Koeffler, MD. He works at the University of California at Los Angeles and Cedars-Sinai Medical Center in Los Angeles.
Use White Pepper Powder For Dandruff
White pepper is mixed with curd and applied on the scalp. When left there for thirty minutes, it helps to prevent the occurrence of dandruff. The mixture should then be washed with water. White pepper is known to improve hair growth as it improves blood flow.
Increased oxygenated blood flow ensures that the scalp gets the necessary nourishment and helps in the strengthening of hair roots. One can use white pepper with a mixture of lime and apply it on hair or make it shiny.
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Black Pepper Oil For Arthritis
Arthritis is a pain due to inflammation in the joints of the bones in the body. Pepper oil is very helpful to cure arthritis and to give relief from the pain. Black pepper essential oil provides powerful anti-oxidant and anti-inflammatory substance when consumed with food. This helps to combat arthritis.
Warm pepper oil, add to a massage oil and massage for 5-7 minutes every night before going to bed to get the best result. You can also mix ground black pepper with sesame oil and heat it for a while. Allow it to cool till it is lukewarm. Apply it on your joints every day. This will also help you get relief from the unbearable arthritis pain.
White Pepper Improves Low Appetite
White pepper is useful in curing conditions, such as low appetite, which is known as anorexia. Stomach disorders, such as diarrhea, colon cancer and constipation are prevented when white pepper is taken daily. Intestinal disorders are also prevented. Stomach enzymes are regulated when white pepper is taken on a daily basis. Toxic elements inside the body are flushed out by white pepper and this regulates the temperature of the stomach.
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