What Are The Side Effects Of Hormone Therapy For Prostate Cancer
Because androgens affect many other organs besides the prostate, can have a wide range of side effects , including:
- loss of interest in sex
Studer UE, Whelan P, Albrecht W, et al. Immediate or deferred androgen deprivation for patients with prostate cancer not suitable for local treatment with curative intent: European Organisation for Research and Treatment of Cancer Trial 30891. Journal of Clinical Oncology 2006 24:18681876.
Zelefsky MJ, Eastham JA, Sartor AO. Castration-Resistant Prostate Cancer. In: Vincent T. DeVita J, Lawrence TS, Rosenberg SA, eds. DeVita, Hellman, and Rosenbergs Cancer: Principles & Practice of Oncology, 9e. Philadelphia, PA: Lippincott Williams & Wilkins 2011.
Smith MR, Saad F, Chowdhury S, et al. Apalutamide and overall survival in prostate cancer. European Urology 2021 79:150158.
Dont Miss: Stage Four Prostate Cancer Prognosis
Prognosis For Prostate Cancer
It is not possible for a doctor to predict the exact course of a disease, as it will depend on each person’s individual circumstances. However, your doctor may give you a prognosis, the likely outcome of the disease, based on the type of prostate cancer you have, the test results, the rate of tumour growth, as well as your age, fitness and medical history.
Prostate cancer often grows slowly and even more aggressive types tend to grow more slowly than other types of cancer. If diagnosed early, prostate cancer has one of the highest five year survival rates.
Should I Have A Psa Test
Because the results of the PSA test are not as reliable as doctors would like, other tests and investigations are needed to diagnose prostate cancer.
A PSA test cannot identify prostate cancer on its own, and changes in PSA levels alone are not a good reason to start treatment.
If you are thinking about asking for a PSA test, it is important that you first discuss whether it is right for you with your GP so you understand what the results might mean.
The Prostate Cancer Risk Management Programme has information on the risks and benefits of the PSA test to help you decide whether or not to have it.
Read Also: What Does The Prostate Gland Do
Biopsy Vs Prostate Mri
A prostate biopsy is a procedure performed to remove samples of suspicious tissue from the prostate and is used to detect prostate cancer. The most common way of performing a prostate biopsy is passing the needle through the wall of the rectum in a procedure known as a transrectal biopsy. Stereotactic Transperineal Prostate Biopsy is performed by comprehensively sampling the prostate through the perineum while the patient is under general anesthesia. The benefits of STPB include:
- An increased ability to identify hiding cancers
- No hospital stay necessary
- Very low level of discomfort
- Virtually no risk of infection from the procedure
The prostate biopsy diagnosis has been around for a while and has proven results, some patients might choose to opt for a more non-invasive alternative such as a prostate MRI.
The main difference between the procedures stems from an MRIs use of magnetic waves to produce an image, as opposed to needle insertion of a prostate biopsy. The prostate MRI can also help find prostate cancer if you previously had elevated or rising PSAs. MRI is comparable in accuracy to prostate biopsy and it can be essential to help determine the extent of the prostate cancer by helping Doctors find out if the cancer has spread. We recommend you talk to your Doctor for more information on whether a prostate MRI or a prostate biopsy is better for your treatment.
Who Is More Likely To Develop Prostate Cancer
Anyone who has a prostate can develop prostate cancer. But certain factors can make you more likely to develop it:
- Age. Your chance of developing prostate cancer increases as you get older. Prostate cancer is rare in people under age 50.
- Family health history. Your risk of prostate cancer is higher if you have a parent, sibling, or child who has or has had prostate cancer.
- Race. African Americans are more likely to get prostate cancer. They’re also more likely to:
- Get prostate cancer at a younger age.
- Have more serious prostate cancer.
- Die from prostate cancer.
Also Check: Why Incontinence After Prostate Surgery
What Should I Do If I Have Prostate Cancer Symptoms
If you are displaying one or more signs of prostate cancer, be sure to promptly consult with a physician. Even benign prostate conditions like prostate enlargement warrant timely medical attention, so dont delay seeking treatment. And, like most other malignancies, prostate cancer is usually more easily treated when it is detected at an early stage.
Medically reviewed by Monica Chatwal, MD.
At Moffitt Cancer Center, we provide a full range of diagnostic testing for prostate cancer. If you have received a prostate cancer diagnosis, we understand that every day counts, and we want to support you every step of the way. Our Urologic Oncology Program includes a multispecialty team that focuses exclusively on evaluating and treating prostate cancer.
Contact Moffitt at or complete a new patient registration form online to speak with one of our specialized oncologists about your symptoms. As Floridas top cancer hospital, were committed to providing all new patients rapid access to a cancer expert within a day of their reaching out.
What About Other Treatments I Hear About
When you have cancer you might hear about other ways to treat the cancer or treat your symptoms. These may not always be standard medical treatments. These treatments may be vitamins, herbs, special diets, and other things. You may wonder about these treatments.
Some of these are known to help, but many have not been tested. Some have been shown not to help. A few have even been found to be harmful. Talk to your doctor about anything youre thinking about using, whether its a vitamin, a diet, or anything else.
You May Like: How To Reduce Prostate Enlargement Naturally
Symptoms Of Prostate Cancer
Though early warning signs of prostate cancer are rare, sometimes men experience symptoms before they are diagnosed. The severity of symptoms may depend on where the cancer is located in the prostate and how advanced it has become. However, having any of these symptoms does not necessarily mean that you have prostate cancer or that the disease has progressed beyond its early stages.
What Are Prostate Tests And How Is Prostate Cancer Diagnosed
Tests which check for prostate cancer include:
- A digital rectal exam . In this exam, your provider feels your prostate for lumps or anything unusual by inserting a lubricated, gloved finger into your rectum.
- A prostate-specific antigen blood test. A high PSA blood level may be a sign of prostate cancer. But many other things can cause high PSA levels, too.
- Imaging tests. These tests may use ultrasound or MRI to make pictures of your prostate.
If these tests show that you might have prostate cancer, the next step is usually a prostate biopsy. A biopsy is the only way to diagnose prostate cancer.
During a biopsy, a doctor uses a hollow needle to remove some prostate tissue. The tissue is studied under a microscope to look for cancer cells.
Don’t Miss: What To Take For Prostate Infection
What Is The Controversy Surrounding Psa Screening
In recent years, there has been some controversy surrounding the PSA test. In 2012, the U.S. Preventive Services Task Force assigned the PSA test a D rating. This meant that the USPSTF concluded the harms that resulted from PSA testing, such as unnecessary biopsies and negative treatment side effects, outweighed the benefits of finding and managing the disease early. This recommendation did not include exceptions for men at increased risk of developing the disease, such as African American men, those with a family history of the disease, and those with BRCA gene mutations. The USPSTF recommendation is important as it guides primary care physicians in preventive care and can impact insurance coverage and reimbursement for screening. Prior to its D rating, the PSA test had an I rating, meaning the USPSTF concluded there was insufficient evidence to assess the pros and cons of testing.
In May 2018, the USPSTF updated their recommendation on PSA screening. In response to new research demonstrating the benefits of PSA screening , an increase in the number of men choosing active surveillance, and advocacy efforts, the USPSTF released a draft recommendation in April 2017 that assigns the PSA test a C rating for men ages 55to 69 . This rating has now been certified official by the task force.
You May Like: Can Kidney Stones Affect Your Prostate
What Are 5 Common Warning Signs Of Prostate Cancer
In many cases, prostate cancer does not produce clear symptoms in its initial stages of development. In fact, many men may have prostate cancer without even realizing it. However, there are some common warning signs that could indicate a person has prostate cancer. Five of the most common ones include:
Of course, these five symptoms are not the only potential warning signs of prostate cancer. Other possible indicators could include weak urine flow, and unexplained pain deep in the groin area when sitting down. If cancer has spread beyond the prostate, a man may also suffer lower body swelling, abnormal urinary or bowel habits, or inexplicable weight loss.
It’s important to note that most of these symptoms are not unique to prostate cancer, and may indicate a different condition that is not life-threatening.
Bladder And Urinary Troubles
A prostate tumor that has grown significantly in size may start to press on your bladder and urethra. The urethra is the passage the carries urine from your bladder out of your body. If the tumor is pressing on your urethra, you might have trouble passing urine.
One of the common areas for prostate cancer to spread to is the bladder, because the two organs are close. This can cause additional problems with urination and bladder function.
Some symptoms your bladder and urethra are being affected by cancer include:
- urinating more frequently
- getting up in the middle of the night to pee
- feeling like you have to urinate often and not actually passing anything
Its not as common, but prostate cancer can also spread to your bowel. The cancer first spreads to the rectum, which is the part of your bowel closest to the prostate gland.
Symptoms of cancer thats spread to the bowels include:
Are There Significant Side Effects Of Treatment
Prostate cancer treatment, whether involving surgery or radiation, can cause a host of short- and long-term side effects. Transient side effects are generally tolerated well. Long-term problems with incontinence and or erectile dysfunction, however, can have a major impact on a mans quality of life. Though estimates vary widely, it is reasonable to assume that such long-term or permanent side effects may occur in significant percentage5 of all patients.
When surgery is performed, a nerve associated with sexual function can be severed. A skilled surgeon may be able to spare the nerve, but there are no assurances. Radiation often damages the nerve, though the onset of symptoms may be delayed by as much as one to two years. You should actively question your physicians about their outcomesspecifically the frequency with which their patients experience long-term problems with incontinence and/or impotency.
You May Like: Guidelines For Bone Scan In Prostate Cancer
How Do You Know If You Have Prostate Cancer
Theres no way of knowing if you have prostate cancer without visiting your doctor, as most men with early prostate cancer dont have any symptoms. And if you do have symptoms they can be caused by other things.
And you cant check for prostate cancer yourself.
You may want to speak to your GP if you’re over 50 , even if you don’t have any symptoms. These are all things that can increase your risk of prostate cancer. Your GP can give more information or tests if necessary.
If youre not sure about what to say to your GP, print and fill out this form and show it to them. This will help you have the conversation.
I thought I could be at risk after learning that African Caribbean men are more likely to get prostate cancer than white men.
What Are The Symptoms Of Prostate Cancer
If you have any symptoms that worry you, be sure to see your doctor right away. They may be caused by conditions other than prostate cancer.
Different people have different symptoms for prostate cancer. Some men do not have symptoms at all.
If you have any of the following symptoms, be sure to see your doctor right away
- Difficulty starting urination.
- Weak or interrupted flow of urine.
- Urinating often, especially at night.
- Trouble emptying the bladder completely.
- Pain or burning during urination.
- Pain in the back, hips, or pelvis that doesnt go away.
Keep in mind that these symptoms may be caused by conditions other than prostate cancer.
Links with this icon indicate that you are leaving the CDC website.
- The Centers for Disease Control and Prevention cannot attest to the accuracy of a non-federal website.
- Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
- CDC is not responsible for Section 508 compliance on other federal or private website.
Don’t Miss: What Is Prostate Gland Hypertrophy
How Does The Doctor Know I Have Prostate Cancer
Prostate cancer tends to grow slowly over many years. Most men with early prostate cancer dont have changes that they notice. Signs of prostate cancer most often show up later, as the cancer grows.
Some signs of prostate cancer are trouble peeing, blood in the pee , trouble getting an erection, and pain in the back, hips, ribs, or other bones.
If signs are pointing to prostate cancer, tests will be done. Most men will not need all of them, but here are some of the tests you may need:
PSA blood test: PSA is a protein thats made by the prostate gland and can be found in the blood. Prostate cancer can make PSA levels go up. Blood tests will be done to see what your PSA level is and how it changes over time.
Transrectal ultrasound : For this test, a small wand is put into your rectum. It gives off sound waves and picks up the echoes as they bounce off the prostate gland. The echoes are made into a picture on a computer screen.
MRI: This test uses radio waves and strong magnets to make detailed pictures of the body. MRI scans can be used to look at the prostate and can show if the cancer has spread outside the prostate to nearby organs.
Prostate biopsy: For a prostate biopsy, the doctor uses a long, hollow needle to take out small pieces of the prostate where the cancer might be. This is often done while using TRUS or MRI to look at the prostate. The prostate pieces are then checked for cancer cells. Ask the doctor what kind of biopsy you need and how its done.
Of : Recognizing The Symptoms
Also Check: What To Say To Someone With Prostate Cancer
What Are The 5 Warning Signs Of Prostate Cancer
Each year, almost 250,000 men in the United States are diagnosed with prostate cancer. As with other forms of cancer, this is a dangerous disease that is more easily treated if detected early. Letâs discuss what may cause prostate cancer, the 5 common warning signs associated with it, and what to do if you suspect that you have it.
Donât Miss: Whatâs The Survival Rate For Prostate Cancer
How Is Prostate Cancer Treated
Your treatment will depend on what kind of cancer cells you have, how far they have spread, your age and general health, and your preferences. At HealthPartners and Park Nicollet, we approach cancer treatment by understanding the impact it has both physically and mentally. So, you and your doctor may decide to manage your cancer with active surveillance or to treat it with surgery or radiation.
If youre over age 80 or have other serious health problems, like heart disease, you may choose not to have treatments to cure your cancer. Instead, you can just have treatments to manage your symptoms. This is called watchful waiting.
If youve already been diagnosed with prostate cancer, choosing treatment for prostate cancer can be confusing. Both urologists and oncologists have the specialty training and expertise to treat prostate cancer. They can work with you develop a treatment plan thats right for you.
Don’t Miss: How High Can Prostatitis Raise Psa
Gleason Score Vs Grade Groups
The International Society of Urological Pathology released a revised prostate cancer grading system in 2014. The grade group system seeks to simplify Gleason scores and give a more accurate diagnosis.
One of the major problems with the Gleason score is that some scores can be made up in different ways. For example, a score of 7 can mean:
- 3 + 4. The 3 pattern is the most common in the biopsy and 4 is the second most common. This pattern is considered favorable intermediate risk.
- 4 + 3. The 4 pattern is the most common in the biopsy and 3 is the second most common. This pattern is considered unfavorable and may mean local or metastatic spread.
So, although both situations give a Gleason score of 7, they actually have very different prognoses.
Heres an overview of how the two grading systems compare:
|grade group 5||910|
Not all hospitals have switched to the grade group system. Many hospitals give both grade group and Gleason scores to avoid confusion until grade groups become more widely used.