The Sperling Prostate Center Advantage
Our philosophy is to match the treatment with the disease. Our BlueLaser 3T mpMRI-Guided Biopsy is the most responsible and accurate way to know your disease before making a treatment decision. We help patients avoid the risk of under-treating aggressive disease, or over-treating insignificant disease that can safely be monitored. We pride ourselves on having attained international recognition for excellence in real-time MRI-guided prostate cancer diagnosis.
If BlueLaser 3T mpMRI detects cancer, a biopsy is essential because prostate cancer may not show early symptoms, though certain warning signs indicate increased prostate cancer risk:
- An elevated or rising PSA blood test result
- An abnormal digital rectal exam
- A family history of prostate cancer or breast cancer
- Being of African-American descent
- Exposure to certain cancer-causing toxins, e.g. Vietnam vets exposed to Agent Orange
- In later stages, prostate cancer may show symptoms such as urinary difficulties, blood in urine, pelvic or back pain, and bone pain. See a doctor if any of these symptoms occur.
Risks Of Prostate Surgery
The risks with any type of radical prostatectomy are much like those of any major surgery. Problems during or shortly after the operation can include:
- Reactions to anesthesia
- Blood clots in the legs or lungs
- Damage to nearby organs
- Infections at the surgery site.
Rarely, part of the intestine might be injured during surgery, which could lead to infections in the abdomen and might require more surgery to fix. Injuries to the intestines are more common with laparoscopic and robotic surgeries than with the open approach.
If lymph nodes are removed, a collection of lymph fluid can form and may need to be drained.
In extremely rare cases, a man can die because of complications of this operation. Your risk depends, in part, on your overall health, your age, and the skill of your surgical team.
Considering Complementary And Alternative Methods
You may hear about alternative or complementary methods that your doctor hasnt mentioned to treat your cancer or relieve symptoms. These methods can include vitamins, herbs, and special diets, or other methods such as acupuncture or massage, to name a few.
Complementary methods refer to treatments that are used along with your regular medical care. Alternative treatments are used instead of a doctors medical treatment. Although some of these methods might be helpful in relieving symptoms or helping you feel better, many have not been proven to work. Some might even be harmful.
Be sure to talk to your cancer care team about any method you are thinking about using. They can help you learn what is known about the method, which can help you make an informed decision.
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Features Of Bph Lesions
BPH is a nodular regional growth with a variegated gross appearance. Nodules of varying sizes may appear anywhere in the prostate, although they are found more commonly in the transitional zone and periurethral areas. The prostatic capsule acts somewhat as a barrier to outward growth, so as nodules grow, they may compress the urethral lumen. No correlation exists between the size of the prostate or prostatic nodules and urethral occlusion.
Transurethral Prostate Hyperthermia: 100% Initial Response Rate
According the Dr. Friedrich Douwes, Medical Director of St. George Hospital in Bad Aibling, Germany, president of the German Oncological Society and author of several hundred scientific articles and books, transurethral prostate hyperthermia has a 100% initial response rate.
Albulets doctor had heard Douwes speak at a medical conference in Las Vegas, NV. Douwes helped to develop the Oncotherm radio-wave hyperthermia treatment, which heats the entire prostate without harming healthy tissue. He has successfully treated thousands of prostate cancer patients, many from the USA. In use for over 25 years, radio-wave hyperthermia is the treatment of choice in Europe for many cancers. When Albulet learned that the treatment took only one week and had a dramatic success rate without side effects, he was elated.
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The Grade Group And Psa Level Are Used To Stage Prostate Cancer
The stage of the cancer is based on the results of the staging and diagnostic tests, including the prostate-specific antigen test and the Grade Group. The tissue samples removed during the biopsy are used to find out the Gleason score. The Gleason score ranges from 2 to 10 and describes how different the cancer cells look from normal cells under a microscope and how likely it is that the tumor will spread. The lower the number, the more cancer cells look like normal cells and are likely to grow and spread slowly.
The Grade Group depends on the Gleason score. See the General Information section for more information about the Gleason score.
- Grade Group 1 is a Gleason score of 6 or less.
- Grade Group 2 or 3 is a Gleason score of 7.
- Grade Group 4 is a Gleason score 8.
- Grade Group 5 is a Gleason score of 9 or 10.
The PSA test measures the level of PSA in the blood. PSA is a substance made by the prostate that may be found in an increased amount in the blood of men who have prostate cancer.
Choosing To Stop Treatment Or Choosing No Treatment At All
For some people, when treatments have been tried and are no longer controlling the cancer, it could be time to weigh the benefits and risks of continuing to try new treatments. Whether or not you continue treatment, there are still things you can do to help maintain or improve your quality of life.
Some people, especially if the cancer is advanced, might not want to be treated at all. There are many reasons you might decide not to get cancer treatment, but its important to talk to your doctors and you make that decision. Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms.
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What Is A Biopsy And How Effective Is It
A needle biopsy is the only way to diagnose prostate cancer when it is suspected. But there are problems with the method most commonly used, called transrectal ultrasound guided biopsy. These problems often lead to inaccurate diagnosis.
For the last two decades, TRUS biopsy has been used to diagnose prostate malignancy. It is actually a blind and random procedure. Specific prostate tumors, especially very small ones, cannot be identified because ultrasound cannot visually detect specific cancer sites. Therefore, it is blind to tumors. In addition, TRUS biopsies tend to target the peripheral aspects of the gland and are likely to miss 30-40% of prostate cancer located in the anterior, midline transition zone, or apex. This is called sampling error. To attempt to overcome it, TRUS biopsies typically average 12-14 needles saturation biopsies use as many as 24 needles. The more needles used, the greater the risk of discomfort, infection, and urinary or sexual side effects while tumors continued to be missed. No other type of tumor cancer is biopsied this way!
What Treatments Are Used In Focal Therapy For Localized Prostate Cancer
Focal therapy uses ablation, which is the use of extreme temperatures to destroy tissue. In focal ablation, the area of the prostate that contains the index lesion is targeted, rather than treating the entire prostate gland. Focal ablation techniques include:
- Cryotherapy: The use of very cold gases passed through needles to freeze and destroy cancer tissue.
- HIFU : The use of high-frequency sound waves directed at the tumor through an ultrasound probe inserted into the rectum. The high intensity waves cause the diseased tissue to heat up and die.
- : A drug called a photosensitizer is injected into the bloodstream. This drug then absorbs light rays directed at the tumor, and produces an active form of oxygen that destroys cancer cells.
- Laser ablation: The use of laser radiation energy pinpointed to a very small area to burn away cancerous tissue. Some laser ablation has the advantage of being able to be performed at the same time as magnetic resonance imaging , allowing very specific targeting and also real-time views of results.
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Hsp90 And Prostate Cancer And Benign Prostatic Hyperplasia
To date, over 200 client proteins have been identified for HSP90. Among them, there are oncoproteins, e.g., the kinases and transcription factors involved in the initiation of the neoplastic process and tumor growth. In neoplastic cells, the client proteins of HSP90 are involved in the transmission of the oncogenic signal, among others, through epithelial growth receptors. In addition, they also participate in the process of angiogenesis receptors), have an anti-apoptotic effect and can mediate the metastasis process of neoplastic cells . The main role of HSP90 family proteins in the neoplastic process is to control the stabilization of oncogenic client proteins and the regulation of the active state . Moreover, depending on HSP90, neoplastic cells maintain their oncogenic activity additionally, this protein acts as a buffer for cellular stress, increased in the course of the neoplastic process . HSP90 also affects the stabilization of the resistance of cancer cells to hormonal therapy, which was confirmed in the study on human breast cancer models . The increase in HSP90 expression is associated with the progression of neoplastic disease and reduces the chance of survival in breast and lung cancer and in the neoplasms of the gastrointestinal tract . On the other hand, the stimulated inactivation of HSP90 paralogs located in different cell compartments has an antitumor effect and regulates calcium homeostasis .
Is A Hot Water Bottle Good For Prostatitis
Bacterial prostatitis may involve antibiotics and medications, while chronic prostatitis may involve medications to reduce pain, discomfort, and inflammation. Home remedies such as warm baths , and hot water bottles or heating pads may also help ease symptoms.
Does warm bath help prostatitis?
The following remedies might ease some symptoms of prostatitis: Soak in a warm bath or use a heating pad. Limit or avoid alcohol, caffeine, and spicy or acidic foods, which can irritate your bladder.
The Future Of Hyperthermia
Hyperthermia is a promising way to improve cancer treatment, but it is largely an experimental technique at this time. It requires special equipment, and a doctor and treatment team who are skilled in using it. Because of that, its not offered in all cancer treatment centers.
Many clinical trials of hyperthermia are being done to better understand and improve this technique. Researchers continue to look at how hyperthermia is best used along with other cancer treatments to improve outcomes.
Studies are also looking at ways to reach deeper organs and other sites that cannot be treated with hyperthermia at this time. Current studies are looking at how it might work to treat many types of cancer, including the following:
Physical Emotional And Social Effects Of Cancer
Cancer and its treatment cause physical symptoms and side effects, as well as emotional, social, and financial effects. Managing all of these effects is called palliative care or supportive care. It is an important part of your care that is included along with treatments intended to slow, stop, or eliminate the cancer.
Palliative care focuses on improving how you feel during treatment by managing symptoms and supporting patients and their families with other, non-medical needs. Any person, regardless of age or type and stage of cancer, may receive this type of care. And it often works best when it is started right after a cancer diagnosis. People who receive palliative care along with treatment for the cancer often have less severe symptoms, better quality of life, and report that they are more satisfied with treatment.
Palliative treatments vary widely and often include medication, nutritional changes, relaxation techniques, emotional and spiritual support, and other therapies. You may also receive palliative treatments similar to those meant to get rid of the cancer, such as chemotherapy, surgery, or radiation therapy.
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High Intensity Focused Ultrasound For Prostate Cancer
HIFU is a treatment that uses high frequency sound waves to destroy prostate cancer cells. The waves create heat that destroys the cancer cells.
You might have HIFU for prostate cancer that hasnt spread outside the prostate or that has come back in the prostate after treatment. It is only available in specific centres in the UK or as part of a clinical trial.
Prostate Cancer Symptoms And Treatment
After a prostate cancer diagnosis, choosing an appropriate treatment path can be incredibly confusing and stressful for you and your loved ones.
Sometime after being diagnosed with prostate cancer you and your doctor will start to discuss your medical management options. Knowing your tumor aggressiveness is critical for understanding if you are safe to pursue active surveillance or if you should pursue one or multiple forms of treatment. Each of the below treatments has pros and cons, so make sure to talk with your doctor, family, and friends to gather as much information as possible to create a plan that is best for you.
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Leading Specialists In Laser Ablation Procedure For Prostate Tumors
Are you, or is someone you love, at risk for prostate cancer? Have you been told that your PSA test results are high and you need a biopsy? Have you had a positive biopsy? Are you exploring alternatives to surgery or radiation?
The world of prostate cancer can be overwhelming, with confusing and conflicting information about the disease and its treatments, but little explaining what is happening inside your own body.
Rest assured. The Sperling Prostate Center team is here to put your mind at ease.
Patient Greyson Quarles tells his story
The Sperling Prostate Center in Florida offers noninvasive advanced imaging as a revolutionary first step in prostate tumor detection and diagnosis. The more you know about what is happening in your body, the more informed and rational your healthcare decisions will be. The best education is having a clear picture of what is going on within your own body. Dr. Sperling and his team will welcome and support you as advanced images are captured, your prostate gland is mapped, and the results are explained to you in a way you can fully understand.
Limitations Of Laser Treatment
- Not many doctors and nurses are trained to use lasers.
- Laser equipment costs a lot of money and is bulky compared with the usual surgical tools used. But advances in technology are slowly helping reduce their cost and size.
- Strict safety precautions must be followed in the operating room when lasers are used. For example, the entire surgical team and the patient must wear eye protection.
- The effects of some laser treatments may not last long, so they might need to be repeated. And sometimes the laser cannot remove all of the tumor in one treatment, so treatments may need to be repeated.
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Treating Prostate Cancer That Has Spread To The Bones
Doctors are studying the use ofradiofrequency ablation to help control pain in men whose prostate cancer has spread to one or more areas in the bones. During RFA, the doctor uses a CT scan or ultrasound to guide a small metal probe into the area of the tumor. A high-frequency current is passed through the probe to heat and destroy the tumor. RFA has been used for many years to treat tumors in other organs such as the liver, but its use in treating bone pain is still fairly new. Still, early results are promising.
What Are The Advantages Of Hifu
Advantages of HIFU include:
- It requires no surgical incisions into your body and doesnt use radiation.
- It can exactly target diseased tissue, leaving non-targeted healthy tissue unharmed.
- Its often an outpatient procedure with a short recovery time. You can usually return to work or your usual routine within a few days.
HIFU has fewer side effects than more invasive types of tumor treatment, including:
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The Stages Of Treatment
Because the stage of your cancer is the most influential factor in how your treatment will progress, weve divided the rest of this article into segments based on the stage of your cancer:
Stage 1 prostate cancer is the least advanced stage. This means your cancer is small and hasnt advanced past your prostate.
In this stage, PSA and Grade Group levels are low. Over 99% of people with prostate cancer caught in this stage survive the effects of cancer for at least 5 years. This means that you can still die of other causes, but you have a less than 1% chance of dying of prostate cancer complications.
for stage 1 prostate cancer usually consists of some combination of active surveillance, surgery, or radiation therapy. You may also be eligible for clinical trials that offer newer treatment techniques.
What Is Hyperthermia Treatment
Hyperthermia is a type of treatment in which body tissue is heated to as high as 113 °F to help damage and kill cancer cells with little or no harm to normal tissue. Hyperthermia to treat cancer is also called thermal therapy, thermal ablation, or thermotherapy.
Different types of techniques may be used to create heat for hyperthermia treatment. These techniques include:
- probes that make energy from microwaves
- heating fluids such as blood or chemotherapy drugs and putting them into the body
- placing the entire body in a heated chamber or hot water bath or wrapping with heated blankets
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