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How Cannabis Affects Prostate Cancer Cells

Dr. Drew On Marijuana: If Pot Cured Cancer, ‘I’d Be High Right Now’

Research shows that prostate cancer cells have higher levels of expression of both CB1 and CB2 receptors than normal cells. To put it another way, the cancer cells have a greater affinity for cannabinoids than normal cells. Laboratory studies have demonstrated that when the cells are treated with a specific cannabinoids, three consequences occur:

  • In general, the cells became less viable and more prone to apoptosis , and
  • Androgen receptor activity on the cancer cell surfaces decreased
  • Two cannabinoids, THC and CBD, discourage the formation of tumor blood vessels needed by prostate cancer tumors to nourish themselves.
  • A very extensive study was conducted by De Petrocellis et al. using both prostate cancer cells in lab containers and prostate cancer tumor cells implanted in mice. Non-THC cannabinoids were thus tested for their biochemical effects on individual cells as well as actual tumor behavior in live animals. The overall results were encouraging, with the authors suggesting that non-THC cannabinoids, and CBD in particular, retard proliferation and cause apoptosis of PCC via a combination of cannabinoid receptor-independent, cellular and molecular mechanisms.

    Natural Cures For Enlarged Prostate

    Treatment of prostatitis includes a variety of practices that incorporate daily supplements and natural remedies. One of the most widely used holistic cures is cayenne pepper, which is reported to alleviate the symptoms of a swollen prostate quickly. Cayenne is also widely used in the treatment of prostate cancer.

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    New Study Reveals Increased Risk Of Certain Cancers Among Marijuana Users

    While smoking marijuana joints poses of same lung cancer risks as tobacco cigarettes due to similar toxins, there are other concerns. Even if a marijuana smoker avoids combustible forms of the drug, there are still dangers.

    There are several studies placing a possible link between . Specifically, these studies address prostate and testicular cancer among male users of the drug.

    A large study of U.S. men ages 15 to 49 was inconclusive when linking marijuana to several types of cancers, except for prostate cancer. The study found that, among participants who were not cigarette smokers, those who smoked marijuana had a higher risk of prostate cancer.

    There have also been three major studies linking cannabis use to a higher risk of testicular cancer. The latest study, published in the journal Cancer Epidemiology, Biomarkers & Prevention, finds that heavy use of marijuana leads to significantly higher risks of developing testicular cancer. Heavy use is defined as using cannabis 50 times or more during a lifetime.

    You can avoid some of the long-term effects of marijuana use by seeking addiction treatment.

    What Can I Drink For An Enlarged Prostate

    There are a number of drinks that are beneficial for the prostate gland when it is enlarged. Green tea can be helpful as it may reduce inflammation, plus it has anti-viral and anti-bacterial properties to keep infections at bay. These are more common amongst men who cannot empty their bladder properly because of an enlarged prostate.

    Although green tea does contain caffeine, which is known to be problematic for sufferers of an enlarged prostate, the quantities are very small. Also, the antioxidant and anti-inflammatory nature of green tea outweigh any negatives.

    Drinking plenty of water is also super important as it reduces the concentration of urine in the bladder thus easing irritation in the area. Id recommend increasing your intake gradually though, to avoid any adverse effects like more frequent urination.

    So, what are the key points you should take away from this?

    • Alcohol can worsen enlarged prostate symptoms in a number of ways and for a number of different reasons too
    • Age, hormones, activity levels and smoking are more likely influence the development of an enlarged prostate than alcohol is
    • Stick to the guidelines regarding alcohol consumption that 16 units a week
    • If you need help reducing your alcohol intake then visit your GP or take a look a look at online resources provided by the NHS and Drink Aware
    • Plain, still water and green tea can be beneficial for an enlarged prostate.

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    Staying Hydrated Helps Prevent Kidney Stones

    The number one natural way to prevent kidney stones is to drink more water. If you are not hydrated, you will not produce enough urine. This can increase the chances of kidney stones because low urine output means the urine is concentrated and less likely to dissolve urine salts that cause kidney stone.

    I recommend that you drink around eight glasses of water each day. If you sweat a lot, exercise or have a history of stones, you may benefit from additional fluids.

    A good way to tell if you are drinking enough water is to look at the color of your urine

    Orange juice and lemonade are also good options to drink because they contain citrate, which prevents stones from forming.

    The Current State Of Cannabinoids And Prostate Cancer

    Beverages to Avoid with Enlarged Prostate | Reduce Symptoms of Benign Prostatic Hyperplasia

    With such promising research evidence that cannabinoids are destructive to prostate cancer cells, what is happening with actual prostate cancer patients? Not much, according to a prostate.net blog:

    There are many stories of people who have used cannabis oil to shrink prostate cancer tumors, and many of the people had success combining the oil with traditional therapies to fight their cancer. The problem with getting hard data and studies is that United States laws make it challenging for clinical studies on the marijuana plant to take place. Plus, there seems to be a lack of funding for the research. The studies that have taken place tend to focus on symptoms rather than the efficacy of the cannabis oil to shrink cancer tumors.

    Yet the research teams who have published their results with laboratory experiments, both in lab containers and animal studies, are clearly calling for clinical trials with patients. They point out that non-THC cannabinoids demonstrate properties that keep the cells from proliferating, spreading, building their own blood supply, and taking up androgens . In addition, the De Petrocellis study found that under certain conditions, cannabinoids had a synergistic effect with chemotherapy or hormone therapy . Such features conjure visions of creative directions in prostate cancer treatment.

    Kis B, Ifrim FC, Buda V, Avram S et al. Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer. 2019 Nov 25 20:5905

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    Let Marijuanadoctorscom Help You Find Prostatitis Symptom Relief

    For some patients, obtaining a medical marijuana card is simple. All it requires is filling out a few forms and making a quick visit to your primary physician. Others may have a more challenging time obtaining their card, especially if their doctor is unwilling to make the recommendation for their own reasons.

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    Is Smoking Marijuana Riskier Than Smoking Tobacco

    Though edibles and other ways of using cannabis are grabbing ever bigger shares of the growing medical cannabis market, many people still consume it the old-fashioned way: by smoking. For that reason, much of the research and discussion around the issue of cannabis and cancer risk are concerned with smoking the plant, and how that compares to smoking cigarettes containing nicotine and tar. Recent research suggests that aside from the fact that both can be lit, burned and inhaled, marijuana and tobacco really arent equivalent.

    When materials of any kind are burned, combustion causes the release of toxins that can be inhaled along with the smoke. Some of these, such as benzene, are carcinogens that can damage various organs, especially the lungs. Thats true for both tobacco cigarettes and for cannabis joints, so simply smoking cannabis can expose someone to the carcinogens that come with combustion, just like smoking cigarettes would do. The question is: How much is that exposure?

    How Can I Reduce My Enlarged Prostate Without Surgery

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    To help control the symptoms of an enlarged prostate, try to:Limit beverages in the evening. Limit caffeine and alcohol. Limit decongestants or antihistamines. Go when you first feel the urge. Schedule bathroom visits. Follow a healthy diet. Stay active. Urinate and then urinate again a few moments later.More itemsApr 13, 2021

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    Q Can Changing My Diet And Keeping Physically Active Help Fight Prostate Cancer

    This is a topic people often call us about. Eating healthily, being physically active and staying a healthy weight is important for general health, but can be especially important for men with prostate cancer.

    Why? Well, firstly because theres strong evidence that being overweight increases the risk of aggressive or advanced prostate cancer.

    Staying a healthy weight may also mean your prostate cancer is less likely to spread after surgery or radiotherapy. And if youre having hormone therapy to treat your prostate cancer, your treatment may be less effective if youre very overweight.

    How Can I Manage Bladder Irritation

    You can manage discomfort by avoiding foods you have identified as bladder irritants. But removing foods from your diet doesnt mean you can never have them again. You might be able to enjoy them in moderation . Drinking plenty of water will help reduce pain from any bladder-irritating foods you might ingest, in moderation or accidentally.

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    How Does Alcohol Affect An Enlarged Prostate

    Enlarged Prostate Signs & Symptoms (& Why They Occur)

    From pints in your local pub, to the red wine in your spaghetti bolognaise, alcohol features in many a weekly routine. In a study completed by the Office for National Statistics in 2017, only 20% of adults said they were teetotal. Despite how often, and how many of us, turn to alcohol though, it can prove problematic. When it is drunk excessively it can increase the risk of developing heart disease, for example, as well as liver disease and strokes. Alcohol can also have a number of negative effects on symptoms of an enlarged prostate.

    Dr. Jen Tan

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