How Testosterone Is Related To Orgasm
Testosterone is seen as a positive regulator of sexual desire together with dopamine, but it has a minima interaction with orgasm. Agents that cause an increase in dopamine can cause a noticeable increase in the frequency of erections. Prolactin does the opposite here, as it is a negative regulator of sexual appetite.
The real ejaculatory and erection process is mediated by Nitric Oxide and Serotonin, as well as other mechanical contractions in the penile and pelvic region.
An Excerpt From Testosterone For Life
The oldest and most strongly held prohibition against testosterone therapy is its use in men previously diagnosed with prostate cancer. The fear has been that even in men who have been successfully treated for prostate cancer, raising testosterone levels will potentially make dormant, or sleeping, cancer cells wake up and start growing at a rapid rate. Thus, the FDA requires all testosterone products to include the warning that T therapy is contraindicated in men with a prior history of prostate cancer.
However, attitudes about this are changing and changing rapidly over just the last few years. The reasons for this are several, including the ongoing re-evaluation of the old belief that raising the concentration of testosterone is to prostate cancer like pouring gasoline on a fire or feeding a hungry tumor. In addition, there is growing recognition that T therapy can provide important benefits to a mans quality of life, so the delicate medical balancing act between potential risk and possible benefit is shifting.
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A number of physicians have told me that they have treated occasional patients with testosterone despite the fact that theyd been treated for prostate cancer in the past. The first people to publish their experience with doing this were Drs. Joel Kaufman and James Graydon, whose article appeared in the Journal of Urology in 2004.
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Intermittent Versus Continuous Hormone Therapy
Most prostate cancers treated with hormone therapy become resistant to this treatment over a period of months or years. Some doctors believe that constant androgen suppression might not be needed, so they advise intermittent treatment. The hope is that giving men a break from androgen suppression will also give them a break from side effects like decreased energy, sexual problems, and hot flashes.
In one form of intermittent hormone therapy, treatment is stopped once the PSA drops to a very low level. If the PSA level begins to rise, the drugs are started again. Another form of intermittent therapy uses hormone therapy for fixed periods of time for example, 6 months on followed by 6 months off.
At this time, it isnt clear how this approach compares to continuous hormone therapy. Some studies have found that continuous therapy might help men live longer, but other studies have not found such a difference.
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Prostate Milking Vs Male Orgasm
Many people experience an orgasm from prostate milking, especially if they masturbate during it.
A person may not be able to distinguish between prostate fluid and ejaculated semen. Prostate fluid is one component of semen. When a male has an orgasm and ejaculates, sperm, prostate fluid, and other fluids present in the ejaculate.
Not all men ejaculate or have an orgasm during prostate milking. Masturbation and other forms of sexual contact make an ejaculation during the massage more likely.
Why Did Our Ancestors Have More Testosterone
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How Soon After Prostate Cancer Treatment Can I Be Sexually Active Again
This will depend on what type of treatment you have had and how you feel. It could be several weeks, for others it may be a lot longer for erections to return. Some men will never be able to keep an erection without the help of artificial methods like medicines or medical devices . If you were having problems having erections before treatment, this will not get better after treatment.
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Vitamin D Deficiency And Risk Of Pca
Research indicates that exposure to UV radiation is inversely correlated with PCa incidence and mortality and that vitamin D protects against prostate cancer . Although the underlying biological mechanisms between vitamin D and PCa may be complex, our dynamic model provides an explanation. Vitamin D may reduces PCa risk by slowing down the age-related declines in testosterone. Studies have shown that vitamin D can increase testosterone levels in males . In addition, vitamin D deficiency is more prevalent among blacks than other racial groups , which may help explain more rapid testosterone declines among blacks, and may also contribute to racial disparities in PCa risk.
In summary, all the factors that are reported to be associated with PCa, as described above, are involved directly or indirectly with levels of testosterone and changes with age. The dynamic model, which proposes that the magnitude of age-related declines in testosterone plays an essential role in the genesis of PCa, may help explain the observed associations between these factors and risk of PCa. As the dynamic model suggests, a risk factor may be in the causal pathway of PCa development through acceleration of age-related declines in testosterone, while protective factors may slow down the process. Observed relationships between the risk/protective factors discussed above and testosterone are consistent with the dynamic model.
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What Is The Prostate
The prostate is a walnut-shaped gland that is part of the male reproductive system. The main function of the prostate is to make a fluid that goes into semen. Prostate fluid is essential for a mans fertility. The gland surrounds the urethra at the neck of the bladder. The bladder neck is the area where the urethra joins the bladder. The bladder and urethra are parts of the lower urinary tract. The prostate has two or more lobes, or sections, enclosed by an outer layer of tissue, and it is in front of the rectum, just below the bladder. The urethra is the tube that carries urine from the bladder to the outside of the body. In men, the urethra also carries semen out through the penis.
Hormone Therapy With Radiotherapy
You have this if:
- your cancer hasnt spread to other parts of the body but is at a high risk of coming back, eg the cancer has grown through the covering of your prostate
- you have a very high prostatic specific antigen level
- you have a high Gleason score
You might have hormone therapy before, during and after radiotherapy. Doctors usually recommend that you have the treatment for between 3 months and 3 years. How long depends on the risk of your cancer coming back and how many side effects you get.
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The Dynamic Model And The Role Of Testosterone In The Development Of Pca
Previous research studies have been limited by static models examining the relationship between testosterone levels and PCa. Most published epidemiological studies measured testosterone at a single point in time, which may contribute to the inconsistent findings in the field.
Our dynamic model may help explain conflicting findings. For example, in a group of individuals with PCa who had higher levels of testosterone than others when they were young, their testosterone levels are relatively higher at the time of cancer diagnosis, although they may already have experienced significant declines in testosterone. If such patients are included in research, high testosterone level will be detected as a risk factor for PCa when compared with controls who have relatively lower peak testosterone at young age . In contrast, if a group of individuals with PCa had lower peak testosterone when they were young, their testosterone level will further decrease by the time of PCa diagnosis. In this scenario, it is not surprising to observe a negative association between testosterone levels and PCa if these patients are compared with the controls whose dynamic change in testosterone levels follow the pattern for most people in a population . If all individuals from Scenario A and Scenario B were analyzed together , no association between testosterone levels and PCa is possible .
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What Are We To Make Of This
Partner sex is probably the most important activity that you can have in your life.
If you cant have that, masturbation isnt even a poor second.
Anything involving people, especially women, is incredibly healthy and valuable.
It can be any activity such as dancing, socializing, hiking anything at all,
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What Are The Side Effects Of Hormone Therapy For Prostate Cancer
Because androgens affect many other organs besides the prostate, ADT can have a wide range of side effects , including:
- loss of interest in sex
Studer UE, Whelan P, Albrecht W, et al. Immediate or deferred androgen deprivation for patients with prostate cancer not suitable for local treatment with curative intent: European Organisation for Research and Treatment of Cancer Trial 30891. Journal of Clinical Oncology 2006 24:18681876.
Zelefsky MJ, Eastham JA, Sartor AO. Castration-Resistant Prostate Cancer. In: Vincent T. DeVita J, Lawrence TS, Rosenberg SA, eds. DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology, 9e. Philadelphia, PA: Lippincott Williams & Wilkins 2011.
Smith MR, Saad F, Chowdhury S, et al. Apalutamide and overall survival in prostate cancer. European Urology 2021 79:150158.
Presentation Of The Hypothesis
We present a novel dynamic mode of the relationship between testosterone and prostate cancer by hypothesizing that the magnitude of age-related declines in testosterone, rather than a static level of testosterone measured at a single point, may trigger and promote the development of prostate cancer.
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How Will I Know That My Hormone Therapy Is Working
Doctors cannot predict how long hormone therapy will be effective in suppressing the growth of any individual mans prostate cancer. Therefore, men who take hormone therapy for more than a few months are regularly tested to determine the level of PSA in their blood. An increase in PSA level may indicate that a mans cancer has started growing again. A PSA level that continues to increase while hormone therapy is successfully keeping androgen levels extremely low is an indicator that a mans prostate cancer has become resistant to the hormone therapy that is currently being used.
Need For Hormonal Treatment Of Prostate Cancer May Not Decrease In Future
Despite facts about prostate cancer incidence, presented in section 4 and despite undeniable proof that population based PSA prostate cancer screening reduces mortality due to prostate cancer , it seems some professional bodies, like U.S. preventive services task force recently advised against screening.
Further, among young UK general practitioners, during non-formal conversation, in year 2012, one can easily hear claims like PSA oh I thought it is NOT for screening, it is only for follow up purposes, only for patients, who have diagnosis of prostate cancer already .
With this recent trend by policy-makers, it seems hopes of urologists, who treat prostate cancer patients, that we will in the future find only very few patients, who will present with stage of disease, where nothing else but hormonal treatment would be possible or hormonal treatment will become necessary during the course of their disease, are dispelled. As it seems focus of attention is turned away from early detection and managing , towards second and third line treatments for advanced disease, testosterone measurement in patients with prostate cancer will become even more important in the future.
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What Causes An Enlarged Prostate
In most men, the prostate gland continues to grow throughout their lives, but it may not become enlarged. While there are several theories, the exact cause of enlarged prostate isn’t known. Some believe that the growth could be the result of a rise in the ratio of estrogen to testosterone in the blood of older men. Others think that it might be the result of a substance called DHT that is made from testosterone building up in the prostate. Still others think that it has to do with dormant cells in the prostate suddenly become active later in life.
The prostate is normally about the size and shape of a walnut and weighs about 20 grams . As men age, the prostate gradually increases in size. Generally, the prostate does not grow beyond about twice its normal size because the outer capsule of the gland restricts expansion. Because of this restriction, further tissue growth compresses against the inside of the gland, which can constrict the urethra and cause urinary symptoms. Prostate enlargement appears to be a normal process because it is so common. The only factor that can prevent prostate enlargement from eventually occurring is the elimination of testosterone. Men who have had their testicles removed or have had diseases that left them unable to produce testosterone do not develop benign prostatic hyperplasia — enlarged prostate — or prostate cancer.
Testosterone As A Drug
The male hormone testosterone can feed the growth of prostate cancer, but in an interesting twist, when given in a very specific way, it may also cause its demise. Drugs that block the action of testosterone are commonly used to treat men with advanced prostate cancer therapy. Cutting off the supply of testosterone to the cancer works for a time, but eventually prostate cancer cells figure out a way around it and begin to grow again. Other drugs work at the molecular level to cut off prostate cancer cells access to testosterone, but their impact is temporary and comes with unpleasant side effects. Men who have long-term hormone ablation have a good response initially, but eventually they become resistant to therapy, and then there arent many options left for them, says prostate cancer expert Samuel Denmeade. These are the men most at risk of dying from prostate cancer.
Men were hugging me because they felt so good. People are clamoring for it, says Denmeade. We get emails from men all over the country and the world. Denmeade says they are still learning about the best way to safely give the therapy. So far, the side effects have been low grade, as long as the treatment is limited to men who are asymptomatic without any pain due to prostate cancer, he says. In some cases, the testosterone therapy makes men feel increased energy, less fatigue and restored sexual function.
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Do High Levels Of Testosterone Cause Prostate Cancer
In 2017, the answer most consistent within the medical and scientific field was, no.
Of course, within medicine, there are no real definites. However, after years of studies, recent analyses would suggest that raised levels of testosterone are likely not associated with prostate cancer.
The2015 Therapeutic Advances in Urology analysis of multiple studies concluded, there remains no clear association with higher testosterone and the development of severity of prostate cancer. Another2015 meta-analysis by the American Urological Association Annual Meeting concluded that there is no link between testosteroneboth natural and prescription and prostate cancer or PSA
Please note that it is still best to consult with a doctor in order to prevent and fight prostate cancer in a way that is most applicable to your situation. As the Journal of Urology discussed in their review, the risk of high T and prostate cancer is not zero, so it should still be considered in certain cases.
Although raised T may not cause prostate cancer, there may still be some link between the two. The risk of prostate cancer increases with age proportionally, testosterone levels decline with age. Is this correlated?
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