Keck School Of Medicine Of Usc Receives $24 Million Gift From Sumner M Redstone
Major grant will support groundbreaking research by David Agus, director of the USC Center for Applied Molecular Medicine and USC Westside Prostate Cancer Center
University of Southern California
The Keck School of Medicine of the University of Southern California has announced a $24 million charitable gift from media executive and philanthropist Sumner M. Redstone. The multi-million dollar gift will support cancer research directed by renowned oncologist David Agus, M.D., professor of medicine at the Keck School of Medicine of USC and director of the USC Center for Applied Molecular Medicine and the USC Westside Prostate Cancer Center.
The donation to the Keck School of Medicine of USC is part of more than $100 million in previously announced charitable grants that Redstone has awarded to fund initiatives in the U.S. and abroad. His contributions have funded research and patient care advancements in cancer, burn recovery and mental health at several major non-profit healthcare organizations, and have provided support for groups that care for impoverished children in Southeast Asia. In addition, Redstone recently donated more than $1 million each to medical research programs at Autism Speaks and to fund scholarships at Harvard College, Harvard Law School and Boston Latin School.
USC has received a portion of the Redstone gift in the form of charitable grants. The remainder of the pledge will be donated over the next three years.
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Select Scientific Initiatives At Usc Norris
Cancer Disparities: The catchment area of Los Angeles County includes a diverse population defined by race/ethnicity, as well as age, immigration status, acculturation, socioeconomic status, language, and access to health services. USC Norris leverages longitudinal data collected over 46 years from the NCI-funded Cancer Surveillance Program as well as expertise in spatial sciences/geographic information system mapping to monitor and assess progress in reducing disparities in the catchment area. Given strengths in basic and population-based disparities in pediatric cancers, adolescent and young adult, and adult cancers, they examine disparities within a lifespan approach. USC Norris is also developing a Cancer Disparities Index to identify and monitor the cancer burden and identify contributors to cancer disparities in the catchment area, increase engagement of underserved individuals and populations in cancer disparities research, and broadly disseminate tools for a national impact on cancer disparities.
* This profile was provided by USC Norris.
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Our team was the first in California to offer the latest robot-assisted surgery in our operating room.
Our doctors have performed more than 6,000 radical prostatectomies .
We offer distinctive services that include minimally invasive surgery through a single-entry point in the stomach.
We are developing ways to increase the accuracy of prostate biopsies through the use of advanced technologies.
Our cancer and urology programs are ranked among the best in the country by U.S. News & World Report.
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Why You Should Listen
David Agus is a medical doctor and a Professor of Medicine at the University of Southern California. However, he is also the founder of a couple of game-changing medical initiatives. In 2006, he co-founded Navigenics with Dietrich Stephan, Ph.D., to form a company that would provide people with their individual genetic information, allowing them to act on any predispositions to disease that they might have and prevent onset. He also founded Oncology.com which was the largest cancer Internet resource and community. Dr. Agus research is focused on the application of proteomics and genomics in the study of cancer, as well as developing new therapeutic treatments for cancer. He serves as Director of the USC Center for Applied Molecular Medicine and the USC Westside Prostate Cancer Center. Agus is also the recipient of several honors and awards, including the American Cancer Society Physician Research Award, a Clinical Scholar Award from the Sloan-Kettering Institute and the International Myeloma Foundation Visionary Science Award.
Usc Norris Westside Cancer Center
The USC Norris Westside Cancer Center offers the most cutting-edge cancer treatment options available for men diagnosed with prostate cancer from some of the nations most respected, recognized and knowledgeable doctors in the field of medical oncology. The Center is advancing the clinical care of prostate cancer through the latest biomedical research, personalized medicine and clinical trials. WCCs personalized medicine means not only treating a patients individual disease, but also treating the individual patient. WCC recognizes that each patient is different both biologically and emotionally. This recognition helps guide the doctors in creating unique treatment solutions for each individual. The WCC is closely tied with the USC Center for Applied Molecular Medicine in order to use current molecular technologies to help care for patients with cancer.
9033 Wilshire Blvd.
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David Agus Takes Helm At Usc Westside Cancer Center And Center For Applied Molecular Medicine
David B. Agus, M.D. brings his talents in researching new treatments for prostate cancer to his role as the director of the new University of Southern California Westside Cancer Center located in Beverly Hills, as well as directing the newly established Center for Applied Molecular Medicine at the USC Health Science Campus. Agus, who recently joined the Keck School of Medicine of USC, is focused on providing the most up-to-date care for patients at the Center, located at 8900 Wilshire Blvd. Dr. David B. Agus This multi-disciplinary center is home to promising and exciting advances in treatment, says Agus. Im delighted and honored to team up with USC, and I look forward to moving closer to the goal of curing this disease. Among Agus methods of advancing prostate cancer research is proteomic technology. By integrating clinical trials, pre-clinical studies and molecularly targeted therapy honing in on molecular and cellular changes specific to cancer he has had success in predicting which patients will respond best to certain anti-cancer therapies. He will lead a team of researchers at the USC Center for Applied Molecular Medicine at the Keck School of Medicine of USC. Agus resume includes serving as director of the Spielberg Family Center for Applied Proteomics and Research Director of the Louis Warschaw Prostate Cancer Center at Cedars-Sinai Medical Center. While there, he focused on factors influencing the development and progression of cancer.
Usc Norris Comprehensive Cancer Center
One of the first eight centers to receive NCI-Designated Cancer Center status, the University of Southern California Norris Comprehensive Cancer Center is a leader in cancer research, education, and patient-centered oncology care. USC Norriss vision is to reduce the burden of cancer for all people. The centers location in the fourth most diverse city in the United States provides an opportunity and a mandate to lead in research that addresses the cancer-related needs and cancer disparities among diverse communities and special populations. To realize this vision, USC Norris members are organized into five multidisciplinary research programs spanning from basic science to translational and clinical science and population science. These highly collaborative programs of laboratory, clinical, and population-based research drive scientific discoveries and foster translation to the clinic and community. USC Norriss cancer training programs are part of the fabric of these efforts, creating a diverse pipeline for the next generation of cancer scientists and clinicians, while its Office of Community Outreach and Engagement is the vehicle by which they understand, engage, and serve the needs of the underserved communities in Los Angeles county and beyond.
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Usc Westside Prostate Cancer Center
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David Agus Md Takes Helm At Usc Westside Cancer Center And Center For Applied Molecular Medicine
Newswise David B. Agus, M.D. brings his talents in researching new treatments for prostate cancer to his role as the director of the new University of Southern California Westside Cancer Center located in Beverly Hills, as well as directing the newly established Center for Applied Molecular Medicine at the USC Health Science Campus.Agus, who recently joined the Keck School of Medicine of USC, is focused on providing the most up-to-date care for patients at the Center, located at 8900 Wilshire Blvd.”This multi-disciplinary center is home to promising and exciting advances in treatment,” says Agus. “I’m delighted and honored to team up with USC, and I look forward to moving closer to the goal of curing this disease.” Among Agus’ methods of advancing prostate cancer research is proteomic technology. By integrating clinical trials, pre-clinical studies and molecularly targeted therapy ” honing in on molecular and cellular changes specific to cancer ” he has had success in predicting which patients will respond best to certain anti-cancer therapies. He will lead a team of researchers at the USC Center for Applied Molecular Medicine at the Keck School of Medicine of USC.
Agus’ resume includes serving as director of the Spielberg Family Center for Applied Proteomics and Research Director of the Louis Warschaw Prostate Cancer Center at Cedars-Sinai Medical Center. While there, he focused on factors influencing the development and progression of cancer.
Research At Usc Norris
USC Norris members are organized into five transdisciplinary research programs: Tumor Microenvironment, Genomic and Epigenomic Regulation, Translational and Clinical Sciences, Cancer Epidemiology, and Cancer Control Research. Through Disease-Specific Research Affinity Groups, scientists across the continuum of cancer research collaborate with Clinical Disease Teams to apply new knowledge to address important cancer problems and ultimately to change the paradigm of cancer prevention and cancer care. Selected transformative achievements include the following.
Basic Science: USC Norris has recently:
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Oncology And Genomics Research
A leading Researcher and entrepreneur in personalized medicine for major diseases like cancer As an oncologist, David Agus’ work has focused on the use of genomics and proteomics to understand individual variations in cancer and response to treatment. He is also the founder of Oncology.com, the largest Internet resource and community for cancer patients, and of Navigenics Inc., a genomics technology and wellness company.
Advanced Treatment And Personalized Care For Prostate Cancer
Prostate cancer affects one in every six men in the United States, and one new case occurs every three minutes. Our world-class prostate cancer experts work together as a team to help you understand the signs of prostate cancer. If you develop prostate cancer, we develop an effective treatment plan that best suits your lifestyle and needs.
We offer a wide range of cutting-edge treatment options, including chemotherapy, radiation and advanced surgeries to remove the prostate gland. Our highly experienced urologists have performed more than 3,000 robotic, minimally invasive surgeries to treat prostate cancer and other conditions.
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Phenelzine Sulfate In Treating Patients With Non
| The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
| Recruitment Status : Active, not recruitingFirst Posted : August 15, 2014Last Update Posted : April 5, 2021 |
| Intervention/treatment | Phase | |
|---|---|---|
| Adenocarcinoma of the ProstateRecurrent Prostate CancerStage I Prostate CancerStage IIA Prostate CancerStage IIB Prostate CancerStage III Prostate Cancer | Drug: phenelzine sulfateOther: laboratory biomarker analysisOther: questionnaire administration | Phase 2 |
PRIMARY OBJECTIVES:
I. To assess the proportion of patients with biochemical recurrent prostate cancer treated with phenelzine who achieve a prostate-specific antigen decline of > = 50% from baseline.
SECONDARY OBJECTIVES:
I. To monitor potential toxicities and/or beneficial effects on quality of life of phenelzine in prostate cancer patients.
II. To assess time to radiographic disease progression for patients with recurrent prostate cancer treated with phenelzine.
III. To collect blood and other samples to study the relationship between MAO activity and prostate cancer.
OUTLINE:
After completion of study treatment, patients are followed up every 3 months for up to 3 years.
Nci Grant Funds New Cancer Center
The National Cancer Institute awarded a $16 million research grant to USC on Monday to bring a new perspective to the study of an old disease: cancer.
USC is one of 12 schools that received grant money from the NCI to set up a research program that utilizes the skills of both biological and physical sciences. The grant will help establish an NCI Physical Sciences-Oncology Center based at USC.
The goal for these centers is to broadly bring perspective to the study of cancer, said Dr. Parag Mallick, assistant professor of research at the Keck School of Medicine.
The five-year award is the first major push to apply skills that mathematicians and physicists have long been using in their fields to cancer research. USCs research team will focus on creating a realistic, multi-scale cancer modeling system, which could be used to predict the effectiveness of various treatments.
Can we identify what treatment option will work? And can we personalize our treatment? Mallick said.
The new approach looks at cancer as a disease affecting particular body systems, rather than a problem of individual cancer cells.
Much of the research in the last 50 years has been focused on understanding the cancer cell rather than controlling the disease, Mallick said.
This is a new wave approach to cancer, Agus said. A new way with new people.
The virtual models will recreate cancer from a molecular scale all the way up to the cancer tumors affecting the host.
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The Center For Applied Molecular Medicine At The Keck School Of Medicine
The USC/Norris Comprehensive Cancer Center, is a national resource for cancer research, treatment, prevention and education. Nearly 200 basic scientists, physicians from the faculty of Keck School of Medicine of USC and several USC professional schools/departments and the College of Letters, Arts and Sciences who are members of the USC/Norris Cancer Center investigate the complex origins and progression of cancer, develop prevention strategies and search for cures. The National Cancer Institute has designated the USC/Norris Cancer Center as one of the nation’s 40 comprehensive cancer centers, a select group of institutions providing leadership in cancer treatment, research, prevention and education. USC/Norris has held this designation since 1973, when it was named as one of the first eight comprehensive cancer centers. Research at USC/Norris is organized into five thematic programs , five translational research programs and a “bridge” program in developmental therapeutics.
Why Mount Sinai
The Center of Excellence for Prostate Cancer provides the most up-to-date diagnosis, treatment, and management of prostate cancer. Our facilities are state-of-the-art. We are part of a full-service health system, which means we can easily provide any referrals you may need. Our doctors and researchers are known for innovation in current and emerging treatments. Our surgeons have special expertise in open, laparoscopic, and robotic prostate surgery.
We provide all treatment approaches for prostate cancer. This includes focal therapy, which targets specific cancer cells. We collaborate with The Tisch Cancer Institute, a National Cancer Institute-designated cancer center, to offer new therapies through clinical trials.
In addition, we use the latest in radiation treatment. We are one of the premier centers for brachytherapy and intensity-modulated radiation therapy . Mount Sinai helped develop brachytherapy. Both of these techniques are high-precision radiation treatments that direct radiation to cancer tissues while protecting normal tissue.
The Center of Excellence for Prostate Cancer provides services at several locations in the Mount Sinai Health System. We also treat prostate cancer at our sport-themed center sponsored by Man Cave Health at 625 Madison Avenue in midtown Manhattan.
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