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What Is Stage 3 Prostate Cancer

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Grade And Risk Category

What are the Treatment Options for Stage 3 Prostate Cancer

The biopsy results will show the grade of the cancer. This is a score that describes how quickly the cancer may grow or spread.

For many years, the Gleason scoring system has been used to grade the tissue taken during a biopsy. If you have prostate cancer, youll have a Gleason score between 6 and 10. A new system has been introduced to replace the Gleason system. Known as the International Society of Urological Pathologists Grade Group system, this grades prostate cancer from 1 to 5 .

Risk of progression

Based on the stage, grade and your PSA level before the biopsy, localised prostate cancer will be classified as having a low, intermediate or high risk of growing and spreading. This is known as the risk of progression. The risk category helps guide management and treatment.

Grading prostate cancer

High risk. The cancer is likely to grow aggressive.

Prostate Cancer Stages Based On Standard Scores

After calculating the TNM categories, your doctors will combine your TNM score, Gleason score and PSA levels to assign of a specific stage to your prostate cancer. Keep in mind that every case is different, and statistics and other recommendations are purely general guidelines.

Stage 1
10 years15 years

*Percentages factor in all stages of prostate cancer. Relative survival rate means the percentage of patients who live x number of years after their initial diagnoses, not after stoppage of treatment.

Prostate Cancer Is One Of The Most Common Types Of Cancer Diagnosed In Men

Learn more about prostate stages here. Here are 10 more facts about prostate cancer. It may grow slowly and its typically treatable. A cancer diagnosis can leave you unable to comprehend anything else your doctor says, but its important to pay attention to what stage of cancer you have. Stage 3 prostate cancer is an advanced but still treatable form of the disease.

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Survival Rates For Prostate Cancer

Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time after they were diagnosed. These rates cant tell you how long you will live, but they may help give you a better understanding of how likely it is that your treatment will be successful.

Keep in mind that survival rates are estimates and are often based on previous outcomes of large numbers of people who had a specific cancer, but they cant predict what will happen in any particular persons case. These statistics can be confusing and may lead you to have more questions. Talk with your doctor about how these numbers may apply to you, as he or she is familiar with your situation.

What Is Stage 3 Cancer

Staging and Grading

Stage 3 cancer is sometimes referred to as locally advanced cancer. In this stage, the tumor may have grown to a specific size, the cancer may consist of multiple tumors, and/or the cancer may have spread to adjacent lymph nodes, organs or tissue. In some cases, stage 3 cancers may be considered metastatic cancers, meaning they may have spread beyond their organ of origin.

Many stage 3 cancers have multiple subcategories, usually designated as stages 3A, 3B and 3C. These subcategories are often determined by the size of the tumors, whether multiple tumors are present and the degree to which the cancer has spread locally.

Liquid cancers, or blood cancers, such as leukemia, lymphoma or multiple myeloma, are staged differently than most other cancers because they may not always form solid tumors. Liquid cancers may be staged by a variety of factors, including:

  • The ratio of healthy blood cells to cancerous cells
  • Whether cancer cells are found in lymph nodes or the diaphragm
  • The degree to which lymph nodes, the liver or spleen may be swollen

Stage 3 cancer is determined in the five most common cancers this way:

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Stage 4 Prostate Cancer Treatment

This is the last stage of prostate cancer and describes a tumor that has spread beyond the seminal vesicles to nearby tissues or organs, such as the bladder, rectum, lymph nodes or bones. At this point, treatment of the whole body with hormonal therapy or systemic therapy is the mainstay of stage 4 prostate cancer treatment. Local therapy with surgery or radiation therapy may be needed to help control symptoms. Proton radiation treatment may be used for advanced or late-stage prostate cancer to shrink tumors or control pain. While treatment can only cure a small percentage of T4 tumors, treatment may still be recommended to prolong or improve quality of life. For these distant stage cancers, the 5-year survival rate is 29%.

Stages Of Prostate Cancer

Doctors combine the T, N, and M results with the Gleason score and PSA level in a process called stage grouping. The system uses Roman numerals from I to IV . The stage helps your doctor choose the best course of treatment for you.

Stage I

  • The cancer is growing in your prostate but hasnât spread beyond it.
  • In most cases, the doctor canât feel the tumor during a DRE or see it in imaging tests.
  • The Gleason score is 6 or less, and the PSA level is less than 10.
  • The tumor is in half or less of one side of the prostate.

Stage IIA

  • The cancer is growing in your prostate but hasnât spread beyond it.
  • The doctor may or may not be able to feel the tumor during a DRE or see it on an imaging test.
  • The tumor can touch more than half of one lobe of the prostate but doesnât involve both lobes.
  • The Gleason score is 7 or less, and the PSA level is less than 20.

Stage IIB

  • The cancer is growing in your prostate but hasnât spread beyond it.
  • The doctor may or may not be able to feel the tumor during a DRE or see it on an imaging test.
  • The tumor can be in one or both lobes of the prostate.
  • The Gleason score is 7, and the PSA level is less than 20.

Stage IIC

  • The cancer hasnt spread beyond the prostate.
  • The doctor may or may not be able to feel the tumor during a DRE or see it on an imaging test.
  • The tumor can be in one or both lobes of the prostate.
  • The Gleason score is 7 or 8, and the PSA level is less than 20.
  • The cancer cells appear more abnormal than in stage IIB.

Stage IIIA

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What Is A 5

A relative survival rate compares people with the same type and stage of cancer to people in the overall population. For example, if the 5-year relative survival rate for a specific stage of prostate cancer is 90%, it means that men who have that cancer are, on average, about 90% as likely as men who dont have that cancer to live for at least 5 years after being diagnosed.

Staging Of Prostate Cancer

Diagnosis of Stage 3 Prostate Cancer

The stage of a cancer describes its size and how far it has spread. The results of your tests help your doctors decide on the stage and plan your treatment.

We understand that waiting to know the stage and grade of your cancer can be a worrying time. We’re here if you need someone to talk to. You can:

Macmillan is also here to support you. If you would like to talk, you can:

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What Are The Symptoms Of Stage 3 Prostatecancer

Because stage 3 prostate cancer is still within the prostate area and does not affect other body parts, symptoms majorly originate from the prostate gland and pelvic area. In some cases, patients may experience systemic symptoms and pain.

Stage 3 symptoms usually include urinary and sexual problems:

The Most Common Symptoms Of Stage 3 Mesothelioma Include:

  • Shortness of breath
  • Fluid buildup
  • Weight loss

As the tumors continue to grow and spread throughout the chest, symptoms will become more problematic. Stage 3 symptoms vary from patient to patient depending on where the cancer is spreading and if the tumor mass damages vital organs. Some patients may experience referred pain felt in the neck, back or shoulders.

A tumor invading the chest wall may cause increased chest pain, while tumors forming around the lung may lead to increased breathing difficulties. Pleural mesothelioma tumors also cause increased pleural fluid, which puts pressure on the lungs. Symptoms and characteristics of stage 3 mesothelioma vary based primarily on cancer type.

Connect with a Top Mesothelioma Specialist

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Stage 3 Prostate Cancer Treatment

Once the cancer is staged, a physician may use this information, along with results from the Gleason Grading System and other tests, to make an informed decision about treatment.

There is no one treatment which can reliably treat stage 3 prostate cancer. The type of treatment given is made on a case by case basis, but will often involve one or a combination of these treatments:

  • Hormone Therapy – known as Androgen Deprivation Therapy , this hormonal treatment reduces the levels of male hormones within the body, and can shrink tumors or reduce their rate of growth.
  • Surgery – radical prostatectomy is a surgical treatment for stage 3 prostate cancer. In this procedure, the prostate gland and seminal vesicles are removed.
  • Radiation Therapy – high energy radiation can be used to shrink tumors and kill cancer cells.

For stage 3 prostate cancer, a common treatment is hormone therapy with radiation therapy.

Prostate Cancer Is A Disease In Which Malignant Cells Form In The Tissues Of The Prostate

Prostate cancer cause defined symptom risk factors

The prostate is agland in the malereproductive system. It lies just below the bladder and in front of the rectum . It is about the size of a walnut and surrounds part of the urethra . The prostate gland makes fluid that is part of the semen.

Prostate cancer is most common in older men. In the U.S., about 1 out of 5 men will be diagnosed with prostate cancer.

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Stage 3 Prostate Cancer Prognosis

A cancer is also staged so that a physician can give a prognosis. The term ‘prognosis’ refers to the likely outcome of the disease.

A reliable prognosis for stage 3 prostate cancer cannot be given. However, with treatment the prognosis is usually good. Factors such as the patients overall health, their Gleason and PSA* score can also influence the course of this disease.*A higher level of prostate-specific antigen may indicate prostate cancer.

The National Cancer Institute survival statistics show that the 5 year survival rate for regional stage prostate cancer is almost 100%.

The NCI use a different staging system to the AJCC TNM system cancers are grouped into categories of ‘local’, ‘regional’ and ‘distant’.

Stage 3 prostate cancer falls into the ‘regional’ group this system also shows that 5 year survivability of stage 3 prostate cancer is almost 100%. This is a similar figure to Stage 1 and Stage 2 prostate cancer.

Prostate Cancer Stages And Other Ways To Assess Risk

After a man is diagnosed with prostate cancer, doctors will try to figure out if it has spread, and if so, how far. This process is called staging. The stage of a prostate cancer describes how much cancer is in the body. It helps determine how serious the cancer is and how best to treat it. Doctors also use a cancer’s stage when talking about survival statistics.

The stage is based on tests described in Tests to Diagnose and Stage Prostate Cancer, including the blood PSA level and prostate biopsy results.

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Consider Choosing Proton Therapy Radiation

Proton therapy is gaining popularity for its ability to more precisely target tumors and reduce radiation damage to healthy tissues and surrounding organs. This treatment has also been shown to result in strong cure rates, reduced side effects and improved long-term outcomes, such as a lower risk of impotence and incontinence.

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An Overview of Gleason 3 4 & Gleason 4 3 Prostate Cancer | Ask A Prostate Expert, Mark Scholz, MD

If breast cancer is diagnosed at an early enough stage, its treatable. Your doctor will want to discuss treatment options as well as the prognosis for bladder cancer. Getting a diagnosis of bladder cancer can be a difficult time. Find the information you need today. Although the percentage of cases in men is much lower than in women, male breast cancer accounts for a por. Prostate cancer is one of the most common types of cancer diagnosed in men. The pancreas is an organ that releases enzymes involved with digestion, and hormones to regular blood sugar levels. One in seven men in the united states will receive a prostate cancer diagnosis during his lifetime. The pancreas is located behind the stomach, so having pancreatic cancer doesnt involve a palpable mass that you can feel. Prostate cancer is a common type of cancer in men, according to the mayo clinic. But hearing the words can still be scary. There are a number of different treatments doctors recommend. Although it is the most commonly diagnosed cancer in american women, breast cancer can impact people of all genders.

Getting a diagnosis of bladder cancer can be a difficult time. Being armed with information is vital to begin the fight. The earlier the detection of prostate cancer, the better the patients chance of survival is. Treatment for bladder cancer depends on your overall health, progression of the c. But hearing the words can still be scary.

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The Grade Group And Psa Level Are Used To Stage Prostate Cancer

The stage of the cancer is based on the results of the staging and diagnostic tests, including the prostate-specific antigen test and the Grade Group. The tissue samples removed during the biopsy are used to find out the Gleason score. The Gleason score ranges from 2 to 10 and describes how different the cancer cells look from normal cells under a microscope and how likely it is that the tumor will spread. The lower the number, the more cancer cells look like normal cells and are likely to grow and spread slowly.

The Grade Group depends on the Gleason score. See the General Information section for more information about the Gleason score.

  • Grade Group 1 is a Gleason score of 6 or less.
  • Grade Group 2 or 3 is a Gleason score of 7.
  • Grade Group 4 is a Gleason score 8.
  • Grade Group 5 is a Gleason score of 9 or 10.

The PSA test measures the level of PSA in the blood. PSA is a substance made by the prostate that may be found in an increased amount in the blood of men who have prostate cancer.

There Are 2 Types Of Staging For Prostate Cancer:

  • The Clinical StageThe clinical stage is based on the results of tests that can be done prior to the surgery. They include the DRE, biopsy, X-rays, CT and/or MRI scans and bone scans. X-rays, bone scans, CT scans and MRI scans may not always be needed. They are recommended based on the PSA level, the size of the cancer, which is determined by its grade and volume and the clinical stage of the cancer.
  • The Pathologic StageThe pathologic stage is based on information found during surgery, plus the laboratory results referred to as pathology, of the prostate tissue removed during surgery. The surgery often includes the removal of the entire prostate and some lymph nodes.One important part of the staging process is determining the grade of the cancer. The grading system is based on the microanalysis of the prostatic tissue. While the stage of the cancer is determined based on the macro appearance of the tumor, in connection with the nearby organs and tissues, the grade of cancer is usually determined after a biopsy, when the cells are analyzed under a microscope.
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    Stage : Prostate Cancer Involves More Of The Prostate And A Lump Is Detectable In An Exam

    This category is divided into two stages: stage 2A and stage 2B.

    In stage 2A, features are like stage 1, with these changes:

    • PSA is at least 10, but less than 20.
    • Gleason score is 6 but can be lower if diagnosis was by needle biopsy for conditions other than cancer.
    • Cancer can be found in one half or less of the prostate lobe or more than one lobe.

    Stage 2B cancer means that:

    • The prostate cancer is more extensive, extending to opposite sides of the prostate. It might be detectable with a digital rectal exam. In this instance, the PSA lower than 20 and the Gleason score is 7, according to the National Cancer Institute.
    • Alternatively, cancer remains undetectable in the digital rectal exam and imaging tests. PSA is lower than 20 and the Gleason score is 7.
    • Yet another way this can manifest is with a Gleason score of 8 or more, PSA at any level, but imaging and DRE do not pinpoint the cancer.

    General Prostate Cancer Survival Rate

    Prostate Cancer Stages &  Options

    According to the American Cancer Society:

    • The relative 5-year survival rate is nearly 100%
    • The relative 10-year survival rate is 98%
    • The 15-year relative survival rate is 91%

    Note: Relative survival rate means the percentage of patients who live amount of years after their initial diagnosis.

    Keep in mind, however, that because the compiled list figures are of cancers diagnosed up to 15 years ago, you may have an even greater chance of survival than these indicate due to advances in prostate cancer treatment technology

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